Results 61 to 70 of about 4,383 (215)
Guanethidine-Resistant Hypertension [PDF]
Circulation, 1968 Resistance of hypertensive patients to large doses of guanethidine is seldom due to defective absorption of the drug, since the existence of adrenergic blockade can be demonstrated in these cases. The effect on the blood pressure of intravenous phenoxybenzamine and norepinephrine, respectively, has been compared in groups of hypertensive ...
G, Sandler +2 more
openaire +2 more sources
Intramural Blood Vessels as a Primary Site of Vascular LUTS
LUTS: Lower Urinary Tract Symptoms, Volume 17, Issue 6, November 2025.ABSTRACT Ischaemia has been considered a primary cause of lower urinary tract symptoms (LUTS). The existing concept is that ischaemic LUTS develops subsequent to structural narrowing of feeder arteries of the LUT due to atherosclerosis. However, the distribution of blood flow within each LUT organ that is regulated by intramural microvasculature should
Hikaru Hashitani, Retsu Mitsui
wiley +1 more source
Immersion of the hand in ice water releases adrenergic vasoconstrictor tone in the ipsilateral temple [PDF]
, 2006 Immersion of the hand in painfully cold water induces cutaneous vasodilatation in the temples, more so ipsilaterally than contralaterally. To investigate the mechanism of this response, guanethidine or saline was administered by transcutaneous ...
Drummond, P.D.
core +1 more source
British Journal of Pharmacology, Volume 182, Issue 19, Page 4535-4552, October 2025.Background and Purpose Although perivascular adipose tissue (PVAT) contains substances with contractile properties, its actions on the vascular tone are associated with the release of anticontractile substances. We hypothesize that procontractile PVAT products also exert direct effects on vascular tone. Experimental Approach Thoracic aortas from Wistar
Leonardo Gomes‐Pereira +1 more
wiley +1 more source
UEG Week 2023 Moderated Posters
, 2023 United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley +1 more source
Drug Interactions with Guanethidine [PDF]
, 1971 In view of the fact that many hypertensive patients on guanethidine receive a number of different drugs, it is essential to determine whether there is any drug interaction.
Ober, Karl Friedrich
core
Guanethidine chemical sympathectomy: spinal cord and sciatic nerve blood flow [PDF]
, 1993 The spinal cord vasculature is innervated by noradrenergic nerve fibers, the role of which in the regulation of regional spinal cord blood flow (RSCBF) is presently unclear.
W. W. Monafo, Y. Kinoshita
core +1 more source
Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi
British Journal of Pharmacology, Volume 182, Issue 15, Page 3669-3687, August 2025.Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia +14 more
wiley +1 more source
The Effects of Guanethidine on the Noradrenaline Content of the Hypothalamus in the Cat and Rat [PDF]
, 1963 Single injections of guanethidine 15 mg./kg. i.p. did not lower the hypothalamic noradrenaline in cats, but, daily injections of 15 mg./kg. s.c. over a 7 day period consistently produced a decrease in the hypothalamic noradrenaline. Attempts to lower the
R Dagirmanjian
core +1 more source
Neurogenic Vascular Responses in Male Mouse Mesenteric Vascular Beds
Journal of Pharmacological Sciences, 2012 Rat mesenteric arteries were maintained by both adrenergic vasoconstrictor nerves and calcitonin gene–related peptide (CGRP) vasodilator nerves. However, functions of these nerves in a pathophysiological state have not fully been analyzed.
Hiroki Fujiwara +8 more
doaj +1 more source