Results 191 to 200 of about 103,749 (273)
Cationic poly(2‐oxazoline)s (POx) have emerged as versatile materials for different biomedical applications. The combination of the pseudo‐peptidic polymer backbone and the amine‐derived cationic motifs results in well‐tolerated polymers with potential benefits for drug and gene delivery as well as antimicrobial development.
Meike N. Leiske
wiley +1 more source
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley +1 more source
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
ABSTRACT Perovskite quantum dots (QDs) have been considered as promising emitters for lighting and display applications, but they suffer from poor thermal stability under operation. Herein, we introduce sub‐micrometer Ag particles to simultaneously enhance the luminescence intensity and thermal stability of perovskite QDs.
Zhihao Feng +5 more
wiley +1 more source
ABSTRACT In this study, three pyrimidine‐5‐carbonitrile derivatives (PNs) were synthesized using a one‐pot multicomponent reaction involving malononitrile, aromatic aldehydes, and an amidine derivative in an aqueous glucose solution as a fully green medium are 2,4‐diamino‐6‐phenylpyrimidine‐5‐carbonitrile (PN‐1), 2,4‐diamino‐6‐(4‐methoxyphenyl ...
Mohammad Salman +5 more
wiley +1 more source
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Electroelution Into a Salt Trap: Reviving an Old‐School Approach to DNA Purification
Electroelution into a salt cushion is a well‐established yet underutilized method of capturing gel‐purified nucleic acids. This Perspective discusses how this traditional method can be reengineered to meet the demands of next‐generation technologies, such as long‐read sequencing.
Ruslan Kalendar +4 more
wiley +1 more source
Polyethylene-grafted poly(hexamethylene guanidine) modified ultra-high molecular weight polyethylene monofilaments and their antimicrobial properties. [PDF]
Zhang W +5 more
europepmc +1 more source
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan +8 more
wiley +1 more source
Guanidino-Aryl Derivatives: Binding to DNA, RNA and G-Quadruplex Structure and Antimetabolic Activity. [PDF]
Margetić D +3 more
europepmc +1 more source

