Results 211 to 220 of about 6,045 (297)

Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas. [PDF]

ChemMedChem
Minneci M, Farkaš B, Rahman A, Kempf A, Nehlmeier I, Pöhlmann S, Rozas I.   +6 more
europepmc   +1 more source

Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt–Jakob Disease MV1 Subtype

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
We present the clinical, pathological and prion biophysical features of three atypical cases of the MV1 subtype of sporadic Creutzfeldt–Jakob disease (sCJD). We propose that these heterozygous cases exist on a spectrum ranging from MM1‐like to VV1‐like phenotypes and recommend that subtyping be performed at pH 6.9 to avoid missing atypical or mixed ...
Satish K. Nemani, Leonardo M. Cortez, Jennifer Myskiw, Ignazio Cali, Stephanie A. Booth, Gerard H. Jansen, Valerie L. Sim   +6 more
wiley   +1 more source

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim, Sandra Liebscher, Rasmus Klintrot, Lorenzo Vallino, Marcelo Masman, Andreas H. Simon, Marianne Hahn, Sven Hennig, Saskia Neubacher, Frank Bordusa, Tom N. Grossmann   +10 more
wiley   +2 more sources

Water-Triggered Direct Air Capture by Strong Organic Bases. [PDF]

ChemSusChem
Grundtvig Utzon A, Lee JW.
europepmc   +1 more source

Exercise‐induced miR‐126 expression improves vascular health in prediabetes: A randomized controlled trial

Experimental Physiology, Volume 111, Issue 6, Page 3026-3038, 1 June 2026.
Abstract In this study, we investigated whether a structured aerobic exercise programme could enhance microRNA‐126 (miR‐126) expression and improve subclinical atherosclerosis markers [carotid intima–media thickness (CIMT) and ankle–brachial index (ABI)] in individuals with prediabetes.
Elif Yildirim Ayaz, Sadrettin Pençe, Sibel Kuraş, Emine Şeyma Denli Yalvaç, Banu Mesci, Özden Ezgi Üner, Fatoş Nimet Kaya, Berna Dincer, Ferruh Kemal Işman, Aytekin Oğuz   +9 more
wiley   +1 more source

Potential Push-Pull Carbon Superbases Based on Methyl Substitution of Rare Tautomers of Imines. [PDF]

Molecules
Raczyńska ED, Gal JF, Maria PC.
europepmc   +1 more source

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

The Journal of Physiology, Volume 604, Issue 11, Page 4225-4246, 1 June 2026.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai, Xijin Xu, Xia Huo, Joost H. N. Schuitemaker, Marijke M. Faas   +4 more
wiley   +1 more source

The Pyruvate-Glyoxalate Pathway as a Toxicity Assessment Tool of Xenobiotics: Lessons from Prebiotic Chemistry. [PDF]

J Xenobiot
Gagné F, André C.
europepmc   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Shared Mechanism, Distinct Outcomes: Transcriptomic Analysis Reveals Differential Modulation of Metabolic and Detoxification Pathways by Neonicotinoid Insecticides. [PDF]

Int J Mol Sci
Colissi-Martins G, Conte FM, Arbo MD.
europepmc   +1 more source