Results 191 to 200 of about 6,480 (239)

Triazole‐Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak, Dariusz Wawrzyniak, Daniel Baranowski   +2 more
wiley   +1 more source

Cycloaddition Reactions of Sulfo-Biginelli Derived Thiadiazines. [PDF]

Org Lett
Hill CL, Sambor M, Yang A, Wipf P.
europepmc   +1 more source

Ovarian Cancer‐Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56bright Subtype

Immunology &Cell Biology, Volume 104, Issue 9, Page 896-905, October 2026.
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo, Glenerson Baptista, Gabriela Rapozo Guimarães, Raissa Carolina Alves da Silva, Adriana Yoshida, Cláudia Rodrigues Tonetti, José Andrés Yunes, Daniela Maira Cardoso, Sophie Derchain, Mariana Boroni, Fernando Guimarães   +10 more
wiley   +1 more source

Modification of the Zeolite Heulandite with N-(3-Triethoxysilylpropyl)guanidines Offers an Effective Approach to Enhancing Its Adsorption Capacity for Heavy Metal Ions. [PDF]

Int J Mol Sci
Adamovich SN, Nalibayeva AM, Abdikalykov YN, Turmukhanova MZ, Filatova EG, Chugunov AD, Ushakov IA, Oborina EN, Rozentsveig IB, Verpoort F.   +9 more
europepmc   +1 more source

Remediation of chronic ammonia effects in common carp by dietary thymol supplementation

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Chronic ammonia toxicity represents a major challenge in intensive aquaculture, often leading to impaired growth and physiological distress. This study evaluated the efficacy of dietary thymol supplementation in mitigating the deleterious effects of chronic ammonia exposure in common carp, Cyprinus carpio. Fish (initial weight: 10.41 ± 0.23 g)
Morteza Yousefi, Seyed Hossein Hoseinifar, Evgeny Vladimirovich Kulikov, Arfenia Semenovna Karamian, Aleksandr Vladimirovich Tkachev, Kristina Viktorovna Shepeleva, Seyyed Morteza Hoseini   +6 more
wiley   +1 more source

Thermally Activated and Nonactivated Excited State Decay of [Cr(dgpy)₂]³. [PDF]

Inorg Chem
Sittel S, Naumann R, Förster C, Huber ME, Meyer J, Heinze K.   +5 more
europepmc   +1 more source

A Blood–Brain Barrier‐Permeable Guanylhydrazone Analogue of the ASIC3 Activator GMQ Inhibits Human Glioblastoma Stem Cell Growth In Vitro

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
The acid‐sensing ion channel 3 (ASIC3), physiologically located in the peripheral nervous system, was found in stem cells of CNS‐located glioblastoma multiforme (GBM CSCs); its chronic activation in the CNS kills dysfunctional GBM CSCs with no effect on ASIC3‐lacking CNS tissues.
Leonardo Maiorana, Nicoletta Collura, Andrea Gotti, Giulia De Leonardis, Greta Donati, Alice Maiocchi, Luciana Marinelli, Andrea Menegon, Pierfausto Seneci   +8 more
wiley   +1 more source

Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules. [PDF]

Molecules
de Souza JVM, Costa NCS, Brasil MCOA, Dos Anjos LR, de Menezes RPB, Zampieri EH, de Lima JS, Velasquez AMA, Scotti L, Scotti MT, Graminha MAS, Gonzalez ERP, Cilli EM.   +12 more
europepmc   +1 more source

Breaking the Ceiling of Boron‐Boron Bonds: Understanding and Fine‐Tuning Basicity in Diborane(4) Complexes

Journal of Computational Chemistry, Volume 47, Issue 24, September 15, 2026.
Diborane(4) can form strong complexes with one or two nitrogen bases, and still behave as a boron base. Complexed with two nitrogen bases, diborane(4) may reach very high proton affinities, overcoming that of the typical 1,8‐bis(dimethylamino)naphthalene super sponge. However, understanding basicity trends is not straightforward, due to the loss of the
Manuel Yáñez, Otilia Mó, M. Merced Montero‐Campillo, Ibon Alkorta   +3 more
wiley   +1 more source

Guanidino-Aryl Derivatives: Binding to DNA, RNA and G-Quadruplex Structure and Antimetabolic Activity. [PDF]

Molecules
Margetić D, Jadrijević-Mladar P, Brozovic A, Tumir LM.   +3 more
europepmc   +1 more source