Results 181 to 190 of about 6,480 (239)

A Machine Learning Approach That Measures Extracellular pH Within an In Vivo Tumor Model Using acidoCEST MRI

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Machine learning models, particularly RFR (random forest regression), provide accurate and computationally efficient tumor pHe estimation from acidoCEST MRI without requiring auxiliary parametric maps. RFR achieved comparable performance to traditional Bloch fitting (RMSE: 0.020 vs.
Alia Khaled, Chetan B. Dhakan, Lucas B. McCullum, Jorge de la Cerda, F. William Schuler, Tianzhe Li, Mark D. Pagel   +6 more
wiley   +1 more source

A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications. [PDF]

J Comput Chem
Lo R, Ganguly B.
europepmc   +1 more source

Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Drosophila behavior/human splicing (DBHS) proteins are involved at nearly every stage of the RNA lifecycle. There are three paralogues in mammals—SFPQ, NONO and PSPC1—which form both homodimer and heterodimers. It is likely that the non‐redundant and overlapping roles of the different DBHS paralogues emerge from their dynamic and combinatorial
Andrew C. Marshall, Isabelle Mohnen, Alejandro Villa Gomez, Archa H. Fox, Gavin J. Knott, Charles S. Bond   +5 more
wiley   +1 more source

Guanidium Unmasked: Repurposing Common Amide Coupling Reagents for the Synthesis of Pentasubstituted Guanidine Bases. [PDF]

J Org Chem
Aho JAS, Mannisto JK, Mattila SPM, Hallamaa M, Deska J.   +4 more
europepmc   +1 more source

Bis(1,3,4-thiadiazolo)-1,3,5-triazinium halides 4.1 Syntheses of azole-substituted guanidines and bis(azolyl)alkanes

ARKIVOC, 2002
Kurt Wermann, Martin Walther, Ernst Anders   +2 more
doaj   +1 more source

Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity. [PDF]

JACS Au
Braun-Cornejo M, Platteschorre M, de Vries V, Bravo P, Sonawane V, Hamed MM, Haupenthal J, Reiling N, Rottmann M, Piet D, Maas P, Diamanti E, Hirsch AKH.   +12 more
europepmc   +1 more source

Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior

Small Structures, Volume 7, Issue 10, October 2026.
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam, Lorenzo Travaglini, Yun X. Chen, Dominic J. Glover   +3 more
wiley   +1 more source

Biological evaluation of amidine derivatives: In vitro cytotoxicity and cellular antioxidant capacity. [PDF]

PLoS One
Pérez-Madrigal MM, Del Valle LJ, Felipe SA, Martín CDMG, Hernández García JI, Saldías C, Funes M, Alemán C, Finn MG, Díaz Díaz D.   +9 more
europepmc   +1 more source

Pressure‐Induced Changes in Intracellular pH Facilitate the Myogenic Response of Rat Small Tail Arteries

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim The myogenic response contributes considerably to blood flow autoregulation. Intracellular pH (pHi) has a substantial impact on small artery contractility. However, the role of putative pHi changes during myogenic constriction is unknown.
Ulrike Krien, Rudolf Schubert
wiley   +1 more source

Aluminum Cations Stabilized by Hybrid N-Heterocyclic Imine Ligand as Catalysts for Guanidine Synthesis from Carbodiimides and Anilines. [PDF]

Chem Asian J
Chang TW, Hung YF, Lin WY, Leung TF.
europepmc   +1 more source