Results 161 to 170 of about 6,480 (239)

Neonicotinoid Levels Exceed EPA Benchmarks in Half of Waterways on Illinois Protected Lands. [PDF]

Bull Environ Contam Toxicol
Hohoff TC, Bilger EE, Gieser R, Davis MA.   +3 more
europepmc   +1 more source

Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins

Protein Science, Volume 35, Issue 11, November 2026.
Abstract De novo protein design often produces thermostable proteins that denature above 100°C, which complicates the analysis of their stability. Thermostable proteins can be unfolded by combined chemical and thermal denaturation followed by global analysis of multiple melting curves.
Vili Lampinen, Osvaldo Burastero, Iara Plácido Guazzelli, Florian Vögele, Francisca Pinheiro, Jan S. Nowak, Maria M. Garcia Alai, Magnus Kjaergaard   +7 more
wiley   +1 more source

Opioid Affinity of Diazacyclic Peptidomimetic Compounds Derived from Reduced Polyamides. [PDF]

Int J Mol Sci
Chaudhari P, Bunnell A, Yegambaram M, Dooley C, Nefzi A.   +4 more
europepmc   +1 more source

Mapping of C5‐Blocking Monoclonal Antibodies Reveals New C5 Inhibitory Epitopes and Novel Modes of C5 Inhibition

Immunology, Volume 179, Issue 3, Page 444-456, November 2026.
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke, Kok Yung Lee, Georgina Elizabeth Menzies, Masashi Mizuno, Bryan Paul Morgan, Wioleta Milena Zelek   +5 more
wiley   +1 more source

Stability of bicyclic guanidine superbases and their salts in water. [PDF]

RSC Adv
Gazagnaire E, Helminen J, Golin Almeida T, Heinonen P, Metsälä M, Kurten T, Kilpeläinen I.   +6 more
europepmc   +1 more source

A Wild Emmer Wheat B3 Transcription Factor Regulates Seed Growth and Nutrient Allocation

Plant, Cell &Environment, Volume 49, Issue 11, Page 7900-7910, November 2026.
ABSTRACT Seed weight (SW) and nutrient allocation are key determinants of yield and grain quality in wheat, yet the regulatory basis of naturally occurring variation in these traits remains poorly resolved. Wild emmer wheat (Triticum dicoccoides), the progenitor of modern wheat, retains extensive eco‐geographically structured genetic diversity that was
Davinder Sharma, Zechariah Haber, Manas R. Prusty, Raz Avni, Mijal Perez, Moshe Ronen, Rakesh Kumar, Arava Shatil‐Cohen, Paz Haboub, Chen Omer, Gilor Kelly, Hadar Aviv, Adi Doron‐Faigenboim, Din Moshe, Weronika Jasinska, Leah Rosental, Eitan Millet, Hanan Sela, Or Sperling, Amir Sharon, Anna Mintz Dub, Yariv Brotman, Nir Sade   +22 more
wiley   +1 more source

Synergistic diselenide/guanidine catalyzed dehydrophosphorylation of 2-nitrobenzhydrols to access C-stereogenic phosphinates. [PDF]

Chem Sci
Gong JY, Zhou PP, Qiao YH, Qi ZC, Zuo QM, Fang QX, Yang SD.   +6 more
europepmc   +1 more source

Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano, Miguel Maldonado, María‐José Camarasa, Sonia de Castro   +3 more
wiley   +1 more source

Photo- and Cobalt-Catalyzed Cycloisomerization of Unsaturated Guanidines, (Iso-)Ureas, and Carbonates. [PDF]

Org Lett
Lindner H, Carreira EM.
europepmc   +1 more source

Novel guanidine derivatives as mechanistic scaffolds for anticancer agents: synthesis, characterization, DNA-binding, and computational studies. [PDF]

RSC Adv
Zaman H, Saeed A, Azam U, Shabir G, Irfan M, Farag B, El-Seedi HR.   +6 more
europepmc   +1 more source