Results 151 to 160 of about 6,045 (297)
Summary High‐throughput molecular studies of museum specimens (museomics) have great potential in biodiversity research, but fungal historical collections have scarcely been examined, leading to no comprehensive methodological assessments. Here we present a whole genome sequencing (WGS) project conducted at the Fungarium of the Royal Botanic Gardens ...
Torda Varga +24 more
wiley +1 more source
Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9
Enzyme assays and computational analyses reveal that human histidine methyltransferases SETD3 and METTL9 have a capacity to catalyze histidine ethylation in the presence of synthetic or in situ produced S‐adenosylethionine (AdoEth) and Se‐adenosylselenoethionine (AdoSeEth) cosubstrates.
Jordi C. J. Hintzen +14 more
wiley +1 more source
Comprehensive Reinvestigation of Carbodiimide Guanylation: HCl-Initiated Access to Tri- and Tetrasubstituted Guanidines. [PDF]
Vlk L +5 more
europepmc +1 more source
New redox‐active oligothioguanidines are developed and used in dehydrogenative P–P coupling reactions and hydroquinone oxidations. Tetrathioguanidino‐ and tetraguanidinobenzenes oxidize high‐potential halogenated hydroquinones faster than relatively low‐potential hydroquinone.
Ute Wild +4 more
wiley +1 more source
Polycomb (Pc), a core component of Polycomb Repressive Complex 1 (PRC1), is largely intrinsically disordered yet forms buffer‐ and concentration‐dependent higher‐order assemblies. Integrative biophysical analysis and cryo‐electron microscopy reveal dynamic, heterogeneous oligomers, whereas AlphaFold modeling suggests that structural organization is ...
Maria Zahid +4 more
wiley +1 more source
DFT Investigation into the Role of Superbases as the Auxiliary Groups in CO<sub>2</sub> Reduction. [PDF]
Glasovac Z, Kovačević B, Margetić D.
europepmc +1 more source
Derives d'acyl-guanidines modulateurs de la voie de signalisation des proteines hedgehog
La présente invention est relative à des dérivés d'acyl-guanidines modulateurs de la voie de signalisation des protéines Hedgehog utilisés à titre de médicaments, notamment pour le traitement de pathologies impliquant un dysfonctionnement ...
Roudaut Hermine +8 more
core
Optimisation of a Novel Class of DNA Gyrase Inhibitors to Improve Antibacterial Activity
This article describes efforts to increase the antibacterial activity of a recently reported class of novel DNA gyrase inhibitors known as the isoquinoline sulphonamides by improving their uptake in bacterial cells. As antibiotic resistance continues to rise, the need for new antibacterials is clear.
Meg I. Ferguson +9 more
wiley +1 more source
Spectral Quantum Chemistry and Infrared Resonance Library for Data-Driven Molecular Spectroscopy. [PDF]
Krishnadas A +3 more
europepmc +1 more source

