The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo +22 more
wiley +1 more source
CO<sub>2</sub>-Responsive Vinyl Polymers: From Synthesis to Application. [PDF]
MoleculesSheraz M, Wang R.
europepmc +1 more source
The Role of Meprins on the Brain Extracellular Matrix and Perineuronal Nets
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Meprin β overexpression is implicated in Alzheimer's Disease. Recent studies identified brevican as a meprin β substrate, and this study demonstrates that meprin α co‐expression enhances meprin β‐mediated brevican cleavage. Further, neurocan and RPTPζ were identified as novel meprin β substrates in an N‐terminomics analysis of meprin β transgenic mice,
Simon Kreiselmaier +13 more
wiley +1 more source
Investigation of Dearomatizing Spirocyclizations and Spirocycle Functionalization En Route to Spirocalcaridines A and B-Some Trials and Tribulations. [PDF]
MoleculesSingh RP +4 more
europepmc +1 more source
Structure and Activity of Class II Lanthipeptides From a Thermophilic Bacterium
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Heterologous coexpression of the lanthipeptide synthetase TlaM from the thermophilic bacterium Thermoactinomyces sp. DSM 45891, with the precursor peptides TlaA1 and TlaA2 in Escherichia coli, resulted in the introduction of four thioether rings in both peptides.
Enleyona Weir +2 more
wiley +1 more source
A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications. [PDF]
J Comput ChemLo R, Ganguly B.
europepmc +1 more source
Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands
ChemMedChem, Volume 21, Issue 13, 14 July 2026.Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki +2 more
wiley +1 more source
Guanidium Unmasked: Repurposing Common Amide Coupling Reagents for the Synthesis of Pentasubstituted Guanidine Bases. [PDF]
J Org ChemAho JAS +4 more
europepmc +1 more source
Steuerung der Rotation eines Guanidiniumkations durch Kation‐π‐Wechselwirkungen
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Ein Lanthanid‐π‐Container wurde für die Bindung eines Guanidiniumkations in dessen aromatischer Kavität mittels Kation‐π‐Wechselwirkungen verwendet. Röntgenkristallographie und Festkörper‐NMR‐Spektroskopie bei schneller Rotation um den magischen Winkel wurden verwendet, um die zugrundeliegenden Wirt‐Gast‐Interaktionen zu untersuchen.
Hannah Busch +12 more
wiley +1 more source
Biological evaluation of amidine derivatives: In vitro cytotoxicity and cellular antioxidant capacity. [PDF]
PLoS OnePérez-Madrigal MM +9 more
europepmc +1 more source