Results 121 to 130 of about 6,480 (239)

Synthesis of 2-Amino-4-pyrimidinones from Resin-Bound Guanidines Prepared Using Bis(allyloxycarbonyl)-Protected Triflylguanidine

open access: yes, 2016
We have synthesized novel heterocyclic compounds from resin-bound guanidines. For this purpose, an amine immobilized on a solid support was acylated with protected amino acids.
Murray Goodman (2652340)   +1 more
core   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

Thiolate Salt Mediated Dynamic Silyl Ether Exchanges for Polymer Network Design and Deconstruction

open access: yesMacromolecular Rapid Communications, EarlyView.
This work introduces thiolate salts as mediators for dynamic silyl ether exchange. This platform enables the synthesis of reprocessable covalent adaptable polymer networks (CANs) and allows for sterically controlled, and tunable deconstruction of silyl ether‐containing thermosets.
Pierce T. Bombard   +9 more
wiley   +1 more source

Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides

open access: yes, 2004
Because of their basicity and hydrogen-bonding properties, guanidines are an important functional group in many biologically active compounds of natural or synthetic origin.
Boguszewski, Paul A.   +2 more
core   +1 more source

A Chemically Recyclable 1,3,5‐Triazine‐Based Epoxy Thermoset Enabled by Nucleophilic Aromatic Substitution Reaction

open access: yesMacromolecular Rapid Communications, EarlyView.
High‐performance 1,3,5‐triazine epoxy networks are prepared via solvent‐free curing and recycled using nucleophilic aromatic substitution (SNAr) chemistry. This robust thermoset undergoes clean depolymerization into well‐defined building blocks for seamless repolymerization, achieving chemical recycling while preserving thermomechanical performance ...
Yi‐Ru Chen   +3 more
wiley   +1 more source

Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines

open access: yes, 2016
We describe the design, synthesis, and antimalarial activity of 60 bis-tertiary amine, bis-2(1H)-imino-heterocycle, bis-amidine, and bis-guanidine series.
Y. Bordat (2463487)   +7 more
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

Solid-Phase Synthesis of Trisubstituted Bicyclic Guanidines via Cyclization of Reduced N-Acylated Dipeptides

open access: yes, 2016
Solid-Phase Synthesis of Trisubstituted Bicyclic Guanidines via Cyclization of Reduced N-Acylated ...
Adel Nefzi (827946)   +5 more
core   +1 more source

Structural and Stability Analysis of de Novo Designed Proteins Incorporating a Plant Self‐Incompatibility Motif

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi   +7 more
wiley   +1 more source

Guanidines encapsulated in zeolite Y and anchored to MCM-41: synthesis and catalytic activity

open access: yes, 2015
The preparation and characterisation of guanidines encapsulated in zeolite Y and anchored to MCM-41 are described. The catalytic activity of the immobilised and free guanidines were tested in the aldol reaction of benzaldehyde with acetone.
Sercheli, R   +3 more
core   +1 more source

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