Results 111 to 120 of about 6,045 (297)

AI/ML Enabled High‐Throughput Design and Synthesis for Energetic Molecules

open access: yesMaterials Genome Engineering Advances, EarlyView.
Novel design methods for a special kind of functional molecules — the energetic molecules—are summarized. Both classic Machine Learning (ML) and Artificial Intelligence (AI) generative models are utilized for the high‐throughput design of these energetic molecules, and a sort of high‐energy low‐sensitivity molecules are obtained.
Wen Qian
wiley   +1 more source

Palladium-Catalyzed One-Pot Synthesis of N-Sulfonyl, N-Phosphoryl, and N-Acyl Guanidines

open access: yes, 2017
An efficient palladium-catalyzed cascade reaction of azides with isonitrile and amines is presented; it offers an alternative facile approach toward N-sulfonyl-, N-phosphoryl-, and N-acyl-functionalized guanidines in excellent yield.
Guanyu Qiao   +5 more
core   +1 more source

Deciphering the soybean root rot pathogen Phytophthora sojae: Signaling pathways, transcriptional regulation, and effector biology

open access: yesNew Plant Protection, EarlyView.
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu   +4 more
wiley   +1 more source

A Versatile One-Pot Synthesis of 1,3-Substituted Guanidines from Carbamoyl Isothiocyanates

open access: yes, 2016
A Versatile One-Pot Synthesis of 1,3-Substituted Guanidines from Carbamoyl ...
Brian R. Linton (1691350)   +3 more
core   +1 more source

Comparison of In‐Gel and SP3 Based Sample Preparation Protocols for LC‐MS/MS Based Proteomics

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Sensitivity, robustness, and reproducibility of sample preparation are main determinants of data quality in bottom‐up mass spectrometry‐based proteomics. To this end, in‐gel protein clean‐up and digestion has been used for decades and is characterized by its robustness and compatibility with harsh lysis conditions.
Luisa Schwarzmüller   +5 more
wiley   +1 more source

Deoxynucleic Guanidines/PNA (DNG/PNA) Chimeras:  Oligonucleoside Analogue Containing Cationic Guanidinium and Neutral Amide Linkages

open access: yes, 2016
Deoxynucleic Guanidines/PNA (DNG/PNA) Chimeras:  Oligonucleoside Analogue Containing Cationic Guanidinium and Neutral Amide ...
Dinesh A. Barawkar (2139472)   +1 more
core   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

open access: yesPest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus   +13 more
wiley   +1 more source

Covalent post-synthetic modification of metal-organic frameworks: A strategy for designing heterogeneous catalysts

open access: yesResults in Chemistry
Covalent post-synthetic modification (PSM) represents a robust and irreversible strategy for precisely engineering the chemical functionality of metal–organic frameworks (MOFs) without compromising their structural integrity or porosity.
Alireza Banan
doaj   +1 more source

Synthesis and characterization of hybrid guanidines and respective metal complexes

open access: yes, 2017
V rámci této diplomové práce byly připraveny nesymetricky tri-substituované hybridní guanidíny nekatalyzovanými reakcemi vybraného aminu s bis[(2,6- diisopropyl)fenyl]karbodiimidem.
Riemlová, Emilie
core  

Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines

open access: yes, 2016
We describe the design, synthesis, and antimalarial activity of 60 bis-tertiary amine, bis-2(1H)-imino-heterocycle, bis-amidine, and bis-guanidine series.
Y. Bordat (2463487)   +7 more
core   +1 more source

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