Results 31 to 40 of about 6,480 (239)

Autocatalytic and oscillatory reaction networks that form guanidines and products of their cyclization

Nature Communications, 2021
So far, only a few chemical oscillators based on organic reactions have been developed. Here, the authors report both autocatalytic and oscillatory reaction networks that form substituted guanidines from thiouronium salts; when coupled to cascade ...
Alexander I. Novichkov, Anton I. Hanopolskyi, Xiaoming Miao, Linda J. W. Shimon, Yael Diskin-Posner, Sergey N. Semenov   +5 more
doaj   +1 more source

New N-Benzenesulfonylguanidine Derivatives and Their Selective Growth Inhibition of Human Breast Cancer Cell Line MCF-7 and Colon Carcinoma HCT-116

Medical Sciences Forum, 2022
Our previous research proved that benzenesulfonylguanidine derivatives display significant cytotoxic activity against human cancer cells. Here, we describe new 1-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)guanidines with cytotoxic activity against HCT-
Aneta Pogorzelska, Jarosław Sławiński, Anna Kawiak   +2 more
doaj   +1 more source

Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species

Molecules, 2018
Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents ...
Aamer Saeed, Alejandra Bosch, Marisa Bettiol, Diana L. Nossa González, Mauricio Federico Erben, Yanina Lamberti   +5 more
doaj   +1 more source

X-ray Structure of Eleven New N,N′-Substituted Guanidines: Effect of Substituents on Tautomer Structure in the Solid State

Crystals
Guanidine-containing molecules are an interesting class of compounds within both medicinal and material sciences. Having knowledge of their tautomerism is key in designing guanidines that interact with biological and chemical receptors.
Vijayaragavan Elumalai, Vaclav Eigner, Nicholas Alexander Janjua, Per-Olof Åstrand, Torkild Visnes, Eirik Sundby, Bård Helge Hoff   +6 more
doaj   +1 more source

Design and synthesis of a photoswitchable guanidine catalyst

Beilstein Journal of Organic Chemistry, 2012
A novel design as well as a straight-forward synthesis for a photoswitchable guanidine catalyst is reported. Intense studies of the photochromic properties demonstrated the reversible switchability of its photosensitive azobenzene moiety. Its activity in
Philipp Viehmann, Stefan Hecht
doaj   +1 more source

One-pot synthesis of dihydropyrimidines via eco-friendly phosphorus derivatives catalysis

Journal of Saudi Chemical Society, 2022
A straightforward, cost effective and eco-friendly protocol for the Biginelli reaction relying on the use of readily available hypophosphorous acid is presented.
Zakaria Moutaoukil, Cyril Ronco, Rachid Benhida   +2 more
doaj   +1 more source

Synthesis of guanidines 19a-d.

, 2018
Synthesis of guanidines 19a-d.
Črtomir Podlipnik (4899181), Masahiro Niikura (1891927), Cinzia Colombo (165760), Leonardo Lo Presti (1367703), Andrew J. Bennet (1755919), Anna Bernardi (1703314)   +5 more
core   +1 more source

Modified Guanidines as Potential Chiral Superbases. 1. Preparation of 1,3-Disubstituted 2-Iminoimidazolidines and the Related Guanidines through Chloroamidine Derivatives

, 2016
Modified guanidines were explored as potential chiral superbases. Thus, chiral 1,3-dimethyl-2-iminoimidazolidines with or without 4,5-diphenyl groups, their guanidinium salts, and the 2-iminoimidazolidines with (S)-1-phenylethyl groups on the ring ...
Keiko Fukuda (2640976), Toshio Isobe (2984835), Tsutomu Ishikawa (1699012)   +2 more
core   +1 more source

Derivatives of the triaminoguanidinium ion, 5. Acylation of triaminoguanidines leading to symmetrical tris(acylamino)guanidines and mesoionic 1,2,4-triazolium-3-aminides

Beilstein Journal of Organic Chemistry, 2017
Depending on the reaction conditions, N,N’,N’’-tris(benzylamino)guanidinium salts can react with carboxylic acid chlorides to form either symmetrical N,N’,N’’-tris(N-acyl-N-benzylamido)guanidines 6 or mesoionic 4-amino-1,2,4-triazolium-3-hydrazinides 7 ...
Jan Szabo, Julian Greiner, Gerhard Maas
doaj   +1 more source

Norbornane-based antibacterial agents: Benzyl and benzoyl substituted guanidines

European Journal of Medicinal Chemistry Reports, 2022
There is a pressing need to develop new antibiotics to replace those rendered ineffective as a result of widespread antimicrobial resistance. Naturally occurring cationic antimicrobial peptides (CAMPs) exhibit broad-spectrum antibacterial activity and ...
Gareth E. Boer, Shane M. Hickey, Alysha G. Elliott, Frederick M. Pfeffer   +3 more
doaj   +1 more source