Results 21 to 30 of about 6,480 (239)

Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

open access: yesPharmaceuticals, 2023
This study examines the properties of novel guanidines, designed and synthesized as histamine H3R antagonists/inverse agonists with additional pharmacological targets.
Marek Staszewski   +12 more
doaj   +1 more source

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
A small library of substituted cyclic guanidine incorporated benzothiazole-6-sulphonamides was synthesized. All obtained compounds were investigated for their inhibitory activity against the key brain-associated human carbonic anhydrase isoform hCA VII ...
Morteza Abdoli   +2 more
doaj   +1 more source

Amino Acylguanidines as Bioinspired Catalysts for the Asymmetric Aldol Reaction

open access: yesMolecules, 2021
The binding and stabilizing effect of arginine residues in certain aldolases served as inspiring source for the development of a family of amino acylguanidine organocatalysts.
Ciril Jimeno
doaj   +1 more source

Novel Selective and Low-Toxic Inhibitor of LmCPB2.8ΔCTE (CPB) One Important Cysteine Protease for Leishmania Virulence

open access: yesBiomolecules, 2022
Leishmaniasis is a highly prevalent, yet neglected disease caused by protozoan parasites of the genus Leishmania. In the search for newer, safer, and more effective antileishmanial compounds, we herein present a study of the mode of action in addition to
Vitor Partite Moreira   +19 more
doaj   +1 more source

Electrocatalytic Desulfurizative Amination of Thioureas to Guanidines

open access: yes, 2023
Guanidine has been known as an important class of N-containing molecules with a wide range of applications. Described here is a selective and efficient electrochemical approach to the synthesis of guanidines from easily accessible thioureas and amines ...
Chunlan Song   +7 more
core   +1 more source

A Comparative Study of Ultrasound Biodiesel Production Using Different Homogeneous Catalysts

open access: yesChemEngineering, 2019
Biodiesel (BD) is a liquid fuel that consists of mono alkyl esters of long chain fatty acids derived from vegetable oil or fat. Recently, biodiesel has received additional attention and intense research has been performed in this field due to its ...
Kiran Shinde, Serge Kaliaguine
doaj   +1 more source

A comparative analysis of virucidal efficiency of biocide agents

open access: yesВопросы вирусологии, 2017
The main groups of biocide agents used for inactivation of bacteria and viruses were studied for their virucidal activity against enveloped (HIV, viral hepatitis C, influenza virus A) and non-enveloped viruses (poliovirus, adenovirus).
N. N. Nosik, D. N. Nosik, A. I. Chizhov
doaj   +1 more source

Investigation of the Phytochemical Composition, Antioxidant Activity, and Methylglyoxal Trapping Effect of Galega officinalis L. Herb In Vitro

open access: yesMolecules, 2020
Galega officinalis L. has been known for centuries as an herbal medicine used to alleviate the symptoms of diabetes, but its comprehensive chemical composition and pharmacological activity are still insufficiently known.
Katarzyna Bednarska   +2 more
doaj   +1 more source

An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents

open access: yesMolecules, 2016
A high-yield one-pot two-step synthesis of 2-aminoimidazoles (2-AI), exploiting an under-air heterocyclodehydration process between α-chloroketones and guanidine derivatives, and using deep eutectic solvents (DESs) as nonconventional, “green” and ...
Martina Capua   +6 more
doaj   +1 more source

Crystal structure of 1,2-bis(2,6-dimethylphenyl)-3-phenylguanidine

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H25N3, the dihedral angles between the planes of the benzene ring and the two substituent dimethylphenyl rings are 60.94 (7)° and 88.08 (7)°, and the dihedral angle between the planes of the two dimethylphenyl rings is 58.01 (7)°
Hongfei Han, Zhiqiang Guo, Xuehong Wei
doaj   +1 more source

Home - About - Disclaimer - Privacy