Results 21 to 30 of about 6,045 (297)
Molecules, 2017 The synthesis and the evaluation as organocatalysts of new chiral guanidines derived from benzimidazoles in the enantioselective α-amination of 1,3-dicarbonyl compounds using di-t-butylazodicarboxylate as aminating agent is herein disclosed.
Llorenç Benavent +3 more
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Molecules, 2019 The screening of more than 30 million compounds derived from 81 small molecule libraries built on 81 distinct scaffolds identified pyrrolidine bis-cyclic guanidine library (TPI-1955) to be one of the most active and selective antiplasmodial libraries ...
David L. Perry +5 more
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Synthesis of an advanced intermediate of alfa-alloenduracididine from allylglycine
Orbital: The Electronic Journal of Chemistry, 2012 α-Alloenduracididine, 3-(2-amino-4,5-dihydro-1Himidazole-4-yl)-2-aminopropionic acid)1 and its diastereoisomer, enduracididine 2, are two nonproteinogenic amino acids isolated in 1968 from Streptomyces fungicidicus as part of a cyclopeptide the ...
Silvia Helena Cardoso +3 more
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An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents
Molecules, 2016 A high-yield one-pot two-step synthesis of 2-aminoimidazoles (2-AI), exploiting an under-air heterocyclodehydration process between α-chloroketones and guanidine derivatives, and using deep eutectic solvents (DESs) as nonconventional, “green” and ...
Martina Capua +6 more
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CrystalsGuanidine-containing molecules are an interesting class of compounds within both medicinal and material sciences. Having knowledge of their tautomerism is key in designing guanidines that interact with biological and chemical receptors.
Vijayaragavan Elumalai +6 more
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Crystal structure of 1,2-bis(2,6-dimethylphenyl)-3-phenylguanidine
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C23H25N3, the dihedral angles between the planes of the benzene ring and the two substituent dimethylphenyl rings are 60.94 (7)° and 88.08 (7)°, and the dihedral angle between the planes of the two dimethylphenyl rings is 58.01 (7)°
Hongfei Han, Zhiqiang Guo, Xuehong Wei
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One-pot synthesis of dihydropyrimidines via eco-friendly phosphorus derivatives catalysis
Journal of Saudi Chemical Society, 2022 A straightforward, cost effective and eco-friendly protocol for the Biginelli reaction relying on the use of readily available hypophosphorous acid is presented.
Zakaria Moutaoukil +2 more
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Synthesis of guanidines 19a-d.
, 2018 Synthesis of guanidines 19a-d.
Črtomir Podlipnik (4899181) +5 more
core +1 more source
MoleculesLeishmaniasis remains an important neglected tropical disease, and current treatments are limited by toxicity, resistance, and low bioavailability. In this study, novel guanidine derivatives were evaluated through an integrated approach, combining in ...
Geovane Dias-Lopes +8 more
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Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species
Molecules, 2018 Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents ...
Aamer Saeed +5 more
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