Medical Sciences Forum, 2022 Our previous research proved that benzenesulfonylguanidine derivatives display significant cytotoxic activity against human cancer cells. Here, we describe new 1-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)guanidines with cytotoxic activity against HCT-
Aneta Pogorzelska +2 more
doaj +1 more source
Synthesis and Activity of Biomimetic Biofilm Disruptors [PDF]
, 2013 Biofilms are often associated with human bacterial infections, and the natural tolerance of biofilms to antibiotics challenges treatment. Compounds with antibiofilm activity could become useful adjuncts to antibiotic therapy.
Böttcher, Thomas +4 more
core +1 more source
Zinc-Catalyzed Guanylation Reaction of Amines to Carbodiimides/Isocyanate Leading to of Guanidines/Urea Derivatives Formation [PDF]
, 2016 [Not ...
Bhattacharjee, J +2 more
core +1 more source
Mechanochemical synthesis of thioureas, ureas and guanidines
Beilstein Journal of Organic Chemistry, 2017 In this review, the recent progress in the synthesis of ureas, thioureas and guanidines by solid-state mechanochemical ball milling is highlighted. While the literature is abundant on their preparation in conventional solution environment, it was not ...
Vjekoslav Štrukil
doaj +1 more source
An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents
Molecules, 2016 A high-yield one-pot two-step synthesis of 2-aminoimidazoles (2-AI), exploiting an under-air heterocyclodehydration process between α-chloroketones and guanidine derivatives, and using deep eutectic solvents (DESs) as nonconventional, “green” and ...
Martina Capua +6 more
doaj +1 more source
Organocatalytic Enantioselective Henry Reactions [PDF]
, 2011 This is an open access article distributed under the Creative Commons Attribution License.A large number of interesting organocatalytic enantioselective protocols have been explored and successfully applied in the last decade.
Herrera, Raquel P. +2 more
core +2 more sources
Crystal structure of 1,2-bis(2,6-dimethylphenyl)-3-phenylguanidine
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C23H25N3, the dihedral angles between the planes of the benzene ring and the two substituent dimethylphenyl rings are 60.94 (7)° and 88.08 (7)°, and the dihedral angle between the planes of the two dimethylphenyl rings is 58.01 (7)°
Hongfei Han, Zhiqiang Guo, Xuehong Wei
doaj +1 more source
Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]
, 2006 Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille +3 more
core +4 more sources
Enantioselective Michael addition of isobutyraldehyde to nitroalkenes organocatalyzed by chiral primary amine-guanidines [PDF]
, 2014 Primary amine-guanidines derived from trans-cyclohexane-1,2-diamines are used as organocatalysts for the enantioselective conjugate addition of isobutyraldehyde to arylated and heteroarylated nitroalkenes.
Chinchilla, Rafael +4 more
core +2 more sources
Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species
Molecules, 2018 Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents ...
Aamer Saeed +5 more
doaj +1 more source