Results 81 to 90 of about 2,442 (194)

Approaches for Mitigating Woody Breast in Commercial Broilers through Nutritional and Management Strategies [PDF]

open access: yes, 2023
Breast myopathies have caused significant economic losses to the poultry industry over the last decade. The induction of woody breast (WB), white striping (WS), and spaghetti meat (SM) have caused textural issues, functional issues, and a decline in ...
Maynard, Clay
core   +3 more sources

Guanidinoacetic Acid as a Precursor of Creatine for Cattle [PDF]

open access: yes, 2015
Creatine serves as an energy-storing molecule in muscle, and in mammals it can be synthesized in the liver from guanidinoacetic acid (GAA). With this study, we evaluated whether GAA supplementation would lead to creatine production in cattle similarly to
Ardalan, M.   +3 more
core   +2 more sources

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, Volume 15, Issue 6, Page 906-913, June 2025.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

Homoarginine, the methylene homologue of arginine, as a substrate of human arginine:glycine amidinotransferase and arginases

open access: yesБюллетень сибирской медицины, 2018
L-homoarginine (hArg) is a non-coding amino acid, the blood level reduction of which is associated with an increased risk of stroke and heart attack.
E. S. Alekseevskaya   +2 more
doaj   +1 more source

Age-Related Changes in Serum Guanidinoacetic Acid in Women

open access: yesPhysiological Research, 2019
Guanidinoacetic acid (GAA) is a fundamental intermediate in cellular bioenergetics, with circulating levels of GAA often reflects disturbances in its conversion due to many intrinsic and extrinsic factors, including gender or age. Here, we evaluated serum GAA in 172 healthy women aged 18 to 65 years, with age found to significantly predict serum GAA ...
A, Olah   +4 more
openaire   +2 more sources

Supplementation with Guanidinoacetic Acid in Women with Chronic Fatigue Syndrome [PDF]

open access: yesNutrients, 2016
A variety of dietary interventions has been used in the management of chronic fatigue syndrome (CFS), yet no therapeutic modality has demonstrated conclusive positive results in terms of effectiveness. The main aim of this study was to evaluate the effects of orally administered guanidinoacetic acid (GAA) on multidimensional fatigue inventory (MFI ...
Sergej Ostojic   +5 more
openaire   +3 more sources

Oxidative stress‐induced changes in wooden breast and mitigation strategies: A review

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract Wooden breast (WB) is a multifactorial muscular abnormality resulting from the interplay between genetic predispositions for rapid growth, physiological stress, and anatomical impairments. This myopathy has been a persistent challenge in the poultry industry since its initial identification a decade ago.
Yaqin Wang   +6 more
wiley   +1 more source

Suppression Effects of Betaine-Enriched Spinach on Hyperhomocysteinemia Induced by Guanidinoacetic Acid and Choline Deficiency in Rats [PDF]

open access: yes, 2014
Betaine is an important natural component of rich food sources, especially spinach. Rats were fed diets with betaine or spinach powder at the same level of betaine for 10 days to investigate the dose-dependent effects of spinach powder supplementation on
Feng Han   +8 more
core   +2 more sources

A creatine efflux transporter in oligodendrocytes

open access: yesThe FEBS Journal, Volume 292, Issue 5, Page 1124-1140, March 2025.
Creatine deficiency leads to severe neurodevelopmental disorders. In the brain, creatine is synthesized by oligodendrocytes to supply neighboring neurons. While SLC6A8 mediates neuronal uptake, the creatine release mechanism was unclear. Our results establish SLC22A15 as a key creatine efflux transporter.
Svenja Flögel   +3 more
wiley   +1 more source

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