Results 1 to 10 of about 320,673 (337)

Underlying charge-transfer mechanism of visible light emission in guanine crystals [PDF]

Communications Chemistry
Biogenic guanine crystals found in various aquatic and terrestrial animals, show unique optical properties that include structural coloration as well as reflectance and have intrigued researchers for over a century.
Aditya Prasun, Ravindra Vishwakarma, Kangkan Sharmah, Ankur Kanti Guha, Ranjit Thakuria, Tridib K. Sarma   +5 more
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Detection of Pathogens and Antimicrobial Resistance Genes at Low Concentration via Electrochemical Oligonucleotide Tags

Engineering Proceedings, 2023
Pathogens can be detected electrochemically by measuring guanine oxidation signals generated from RNA or DNA hybridized to a biosensor working electrode. However, the associated limit of detection (LOD) is not sufficiently low for widespread clinical use.
Neil Gordon, Raj Bawa, Garry Palmateer
doaj   +1 more source

Synthesis and Characterization of New Guanine Complexes of Pt(IV) and Pd(II) by X-ray Diffraction and Hirshfeld Surface Analysis

Crystals, 2021
The aim of the work was to synthesize new perspective compounds of palladium and platinum with nitrogenous bases (guanine), promising for use in biomedicine and catalysis. The article describes the synthesis of new [PdCl2(HGua)2]Cl2·H2O and [PtCl5(HGua)]·
Anton Petrovich Novikov, Mikhail Alexandrovich Volkov, Alexey Vladimirovich Safonov, Mikhail Semenovich Grigoriev, Evgeny Vladilenovich Abkhalimov   +4 more
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Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms

Frontiers in Pharmacology, 2021
Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy.
Natale Belluardo, Giuseppa Mudò, Valentina Di Liberto, Monica Frinchi, Daniele F. Condorelli, Ugo Traversa, Francisco Ciruela, Francisco Ciruela, Renata Ciccarelli, Renata Ciccarelli, Patrizia Di Iorio, Patrizia Di Iorio, Patricia Giuliani, Patricia Giuliani   +13 more
doaj   +1 more source

Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions [PDF]

International Journal of Molecular Sciences, 2020
Recently, we reported an inhibitory effect of guanine substitutions on the conformational switch from antiparallel to parallel quadruplexes (G4) induced by dehydrating agents. As a possible cause, we proposed a difference in the sensitivity of parallel and antiparallel quadruplexes to the guanine substitutions in the resulting thermodynamic stability ...
Klára Bednářová, Michaela Vorlíčková, Daniel Renčiuk   +2 more
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A Novel Guanine Elicitor Stimulates Immunity in Arabidopsis and Rice by Ethylene and Jasmonic Acid Signaling Pathways

Frontiers in Plant Science, 2022
Rice sheath blight (ShB) caused by Rhizoctonia solani is one of the most destructive diseases in rice. Fungicides are widely used to control ShB in agriculture.
Lulu Wang, Haoqi Liu, Ziyi Yin, Yang Li, Chongchong Lu, Qingbin Wang, Xinhua Ding   +6 more
doaj   +1 more source

N-Edited Guanine Isosteres

The Journal of Organic Chemistry, 2023
Guanine is one out of five endogenous nucleobases and of key interest in drug discovery and chemical biology. Hitherto, the synthesis of guanine derivatives involves lengthy multistep sequential synthesis of low overall diversity, resulting in the quest for innovation. Using a "single-atom skeletal editing" approach, we designed 2-aminoimidazo[2,1-f][1,
Xin Li, Marina Diguele Romero, Sona Tcaturian, Katarzyna Kurpiewska, Alexander Dömling   +4 more
openaire   +3 more sources

Concurrent use of rabacfosadine and L‐asparaginase for relapsed or refractory multicentric lymphoma in dogs

Journal of Veterinary Internal Medicine, 2020
Background Rabacfosadine (RAB), a novel antineoplastic agent conditionally licensed for the treatment of lymphoma in dogs, is efficacious in both naïve and previously treated dogs.
Jacob R. Cawley, Zachary M. Wright, Karri Meleo, Gerald S. Post, Craig A. Clifford, Kathryn R. Vickery, David M. Vail, Philip J. Bergman, Douglas H. Thamm   +8 more
doaj   +1 more source

Simultaneous Determination of Four DNA bases at Graphene Oxide/Multi-Walled Carbon Nanotube Nanocomposite-Modified Electrode

Micromachines, 2020
In this study, we developed a modified glassy carbon electrode (GCE) with graphene oxide, multi-walled carbon nanotube hybrid nanocomposite in chitosan (GCE/GO-MWCNT-CHT) to achieve simultaneous detection of four nucleobases (i.e., guanine (G), adenine ...
Shuting Wang, Celia Ferrag, Meissam Noroozifar, Kagan Kerman   +3 more
doaj   +1 more source

Fluorescence Assay for Detecting Four Organophosphorus Pesticides Using Fluorescently Labeled Aptamer

Sensors, 2022
In this work, we reported a rapid and sensitive fluorescence assay in homogenous solution for detecting organophosphorus pesticides by using tetramethylrhodamine (TAMRA)-labeled aptamer and its complementary DNA (cDNA) with extended guanine (G) bases ...
He Li, Xue Huang, Jingcheng Huang, Mengyuan Bai, Mengjiao Hu, Yemin Guo, Xia Sun   +6 more
doaj   +1 more source