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Tautomerism of Guanine Analogues [PDF]
Biomolecules, 2020 Tautomerism of nucleic acid (NA) bases is a crucial factor for the maintenance and translation of genetic information in organisms. Only canonical tautomers of NA bases can form hydrogen-bonded complexes with their natural counterparts. On the other hand, rare tautomers of nucleobases have been proposed to be involved in processes catalysed by NA ...
Jakub Radek Štoček +1 more
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Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions [PDF]
International Journal of Molecular Sciences, 2020 Recently, we reported an inhibitory effect of guanine substitutions on the conformational switch from antiparallel to parallel quadruplexes (G4) induced by dehydrating agents. As a possible cause, we proposed a difference in the sensitivity of parallel and antiparallel quadruplexes to the guanine substitutions in the resulting thermodynamic stability ...
Klára Bednářová +2 more
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Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites [PDF]
Journal of the American Chemical Society, 2022 Highly reflective crystals of the nucleotide base guanine are widely distributed in animal coloration and visual systems. Organisms precisely control the morphology and organization of the crystals to optimize different optical effects, but little is known about how this is achieved.
Pinsk, Noam +11 more
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Products of Oxidative Guanine Damage Form Base Pairs with Guanine [PDF]
International Journal of Molecular Sciences, 2020 Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2,4-triamino-5(2H)-oxazolone (Oz), guanidinoformimine (Gf), guanidinohydantoin/iminoallantoin (Gh/Ia ...
Katsuhito Kino +4 more
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Modulation of guanine deaminase [PDF]
Biochemical Journal, 1973 1. Guanine deaminases purified from the 15000g supernatant fraction of iso-osmotic sucrose homogenates of rat and mouse liver and brain were tested for the influence of GTP and allantoin. 2. The suffixes A and B were assigned to the isoenzyme fractions eluted from DEAE-cellulose with the lower and the higher molarity of eluent respectively. Isoenzyme A
K. Sree Kumar +2 more
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Calculating Hyperfine Couplings in Large Ionic Crystals Containing Hundreds of QM Atoms: Subsystem DFT is the Key [PDF]
, 2013 We present an application of the linear scaling Frozen Density Embedding (FDE) formulation of subsystem DFT to the calculation of isotropic hyperfine coupling constants (hfccs) of atoms belonging to a guanine radical cation embedded in a guanine ...
Close, David M. +3 more
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Nickel(II)-catalysed oxidative guanine and DNA damage beyond 8-oxoguanine [PDF]
, 2007 Oxidative DNA damage is one of the most important and most studied mechanisms of disease. It has been associated with a range of terminal diseases such as cancer, heart disease, hepatitis, and HIV, as well as with a variety of everyday ailments.
Kelly, Michele C. +3 more
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Structure and singly occupied molecular orbital analysis of anionic tautomers of guanine [PDF]
, 2008 Recently we reported the discovery of adiabatically bound anions of guanine which might be involved in the processes of DNA damage by low-energy electrons and in charge transfer through DNA.
Abdoul-Carime +42 more
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Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives [PDF]
Proceedings of the National Academy of Sciences, 2015 Significance Guanine-rich nucleic acids fold into a four-stranded structure named G-quadruplex that has implications in essential cellular processes, pharmaceutical applications, and nanodevices. We found a unique type of G-quadruplex that contains a G-vacancy and is stabilized by guanine derivatives such as te physiological concentration of ...
Xin-min Li +7 more
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Reductionsproducte aus Guanin [PDF]
Berichte der deutschen chemischen Gesellschaft, 1901 n ...
Tafel, Julius, Ach, Benno
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