Results 1 to 10 of about 201,610 (282)
Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites [PDF]
Journal of the American Chemical Society, 2022 Highly reflective crystals of the nucleotide base guanine are widely distributed in animal coloration and visual systems. Organisms precisely control the morphology and organization of the crystals to optimize different optical effects, but little is ...
Noam Pinsk +11 more
semanticscholar +4 more sources
Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives [PDF]
Proceedings of the National Academy of Sciences, 2015 Significance Guanine-rich nucleic acids fold into a four-stranded structure named G-quadruplex that has implications in essential cellular processes, pharmaceutical applications, and nanodevices. We found a unique type of G-quadruplex that contains a G-vacancy and is stabilized by guanine derivatives such as te physiological concentration of ...
Xin-min Li +7 more
semanticscholar +4 more sources
Generation, repair and replication of guanine oxidation products
Genes and Environment, 2017 Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication.
Katsuhito Kino +4 more
doaj +2 more sources
Biomineralization and Properties of Guanine Crystals
Molecules, 2023 Guanine crystals with unique optical properties in organisms have been extensively studied and the biomineralization principles of guanine are being established.
Haoxin Hu, Rongrong Xue, Fenghua Chen
doaj +3 more sources
Engineering Proceedings, 2023 Pathogens can be detected electrochemically by measuring guanine oxidation signals generated from RNA or DNA hybridized to a biosensor working electrode. However, the associated limit of detection (LOD) is not sufficiently low for widespread clinical use.
Neil Gordon, Raj Bawa, Garry Palmateer
doaj +1 more source
Tautomerism of Guanine Analogues [PDF]
Biomolecules, 2020 Tautomerism of nucleic acid (NA) bases is a crucial factor for the maintenance and translation of genetic information in organisms. Only canonical tautomers of NA bases can form hydrogen-bonded complexes with their natural counterparts. On the other hand, rare tautomers of nucleobases have been proposed to be involved in processes catalysed by NA ...
Jakub Radek Štoček +1 more
openaire +4 more sources
Crystals, 2021 The aim of the work was to synthesize new perspective compounds of palladium and platinum with nitrogenous bases (guanine), promising for use in biomedicine and catalysis. The article describes the synthesis of new [PdCl2(HGua)2]Cl2·H2O and [PtCl5(HGua)]·
Anton Petrovich Novikov +4 more
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Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions [PDF]
International Journal of Molecular Sciences, 2020 Recently, we reported an inhibitory effect of guanine substitutions on the conformational switch from antiparallel to parallel quadruplexes (G4) induced by dehydrating agents. As a possible cause, we proposed a difference in the sensitivity of parallel and antiparallel quadruplexes to the guanine substitutions in the resulting thermodynamic stability ...
Klára Bednářová +2 more
openaire +2 more sources
Frontiers in Pharmacology, 2021 Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy.
Natale Belluardo +13 more
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Products of Oxidative Guanine Damage Form Base Pairs with Guanine [PDF]
International Journal of Molecular Sciences, 2020 Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2,4-triamino-5(2H)-oxazolone (Oz), guanidinoformimine (Gf), guanidinohydantoin/iminoallantoin (Gh/Ia ...
Katsuhito Kino +4 more
openaire +3 more sources