Results 181 to 190 of about 283,665 (235)

Designing Epigenetic Clocks for Wildlife Research

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The applications of epigenetic clocks – statistical models that predict an individual's age based on DNA methylation patterns – are expanding in wildlife conservation and management. This growing interest highlights the need for field‐specific design best practices.
Levi Newediuk   +5 more
wiley   +1 more source

Quencher-Free Fluorescence Monitoring of G-Quadruplex Folding. [PDF]

open access: yesACS Omega
Parada Z   +3 more
europepmc   +1 more source

Ancient Microbiomes as Mirrored by DNA Extracted From Century‐Old Herbarium Plants and Associated Soil

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Numerous specimens stored in natural history collections have been involuntarily preserved together with their associated microbiomes. We propose exploiting century‐old soils occasionally found on the roots of herbarium plants to assess the diversity of ancient soil microbial communities originally associated with these plants.
Gianluca Grasso   +7 more
wiley   +1 more source

A DNP-Supported Solid-State NMR Approach to Study Nucleic Acids In Situ Reveals Berberine-Stabilized Hoogsteen Structures in Mitochondria. [PDF]

open access: yesAngew Chem Int Ed Engl
Krafčíková MD   +8 more
europepmc   +1 more source

Independent Avian Epigenetic Clocks for Ageing and Development

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Information on individual age is a fundamental aspect in many ecological and evolutionary studies. However, accurate and non‐lethal methods that can be applied to estimate the age of wild animals are often absent. Furthermore, since the process of ageing is accompanied by a physical decline and the deterioration of biological functions, the ...
Ayke Haller   +3 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

open access: yesAging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji   +15 more
wiley   +1 more source

Exploring recent advances in signaling pathways and hallmarks of uveal melanoma: a comprehensive review. [PDF]

open access: yesExplor Target Antitumor Ther
Banimohammad M   +9 more
europepmc   +1 more source

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

open access: yesAging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang   +8 more
wiley   +1 more source

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