Results 171 to 180 of about 369,753 (339)

Lysosome-related organelles orchestrate guanine crystal formation in pigment cells. [PDF]

Proc Natl Acad Sci U S A
Gorelick-Ashkenazi A, Barzilay Y, Lerer-Goldshtein T, Olender T, Eyal Z, Glaser M, Broder Y, Mishol N, Deis R, Kedmi M, Gur D.   +10 more
europepmc   +1 more source

Guanine [PDF]

, 2019
openaire   +1 more source

Site-specific ribozyme-mediated alkylation of DNA substrates. [PDF]

Nucleic Acids Res
He Y, Wilson TJ, Deng J, Luo Y, Yan K, Xie Y, Lilley DMJ, Huang L.   +7 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo

Journal of Bacteriology, 2016
Eric M. Kofoed, D. Yan, A. Katakam, M. Reichelt, B. Lin, Janice Kim, Summer Park, Shailesh V. Date, I. Monk, M. Xu, Cary D. Austin, T. Maurer, Man-Wah Tan   +12 more
semanticscholar   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

The Molecular Basis of Growth Control in Guanine Crystals. [PDF]

Small
Brenman-Begin D, Church JR, Sahoo S, Eyal Z, Biran I, Kampf N, Barzilay Y, Kossoy A, Houben L, Sapir L, Hirshberg B, Gur D.   +11 more
europepmc   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

iNew Medicine, EarlyView.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu, Zhicheng Yu, Yang Zhang, Hui Hong, Xiaoli Wang, Shan Jiang, Ying Zhou, Cheng Peng, Hongbo Chen   +8 more
wiley   +1 more source

Canonical and noncanonical forms of G4 DNA at cluster III of the BCL6 breakpoint region could lead to chromosomal translocation in DLBCL. [PDF]

J Biol Chem
Javadekar SM, Das S, Hanumegowda SM, Kumari S, Choudhary B, Raghavan SC.   +5 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source