Nano‐Phase Separation and Analyte Binding in Aptasensors Investigated by Nano‐IR Spectroscopy
An atomic force microscopy ‐ infrared spectroscopy (AFM‐IR) study on the fabrication of an aptamer‐based biosensor revealed the formation of nanodomains rich in DNA aptamers and blocking polyethylene glycol (PEG) molecules. Single‐molecule spectroscopy of the analyte protein is also reported.
Nafiseh Samiseresht+5 more
wiley +1 more source
Structurally Similar Mycotoxins Aflatoxin B<sub>1</sub> and Sterigmatocystin Trigger Different and Distinctive High-Resolution Mutational Spectra in Mammalian Cells. [PDF]
Thongararm P+7 more
europepmc +1 more source
Human hypoxanthine-guanine phosphoribosyltransferase. Evidence for tetrameric structure.
J A Holden, William N. Kelley
openalex +1 more source
Rare GNAO1 Variant Presenting with Deep Brain Stimulation‐Responsive Jaw‐Opening Dystonia
Movement Disorders Clinical Practice, EarlyView.
Fabian Maass+4 more
wiley +1 more source
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos+2 more
wiley +1 more source
Methylmap: visualization of modified nucleotides for large cohort sizes. [PDF]
Coopman E+3 more
europepmc +1 more source
Recent Advances in Biosensors Based on Hybridization Chain Reaction and Silver Nanoclusters
This review explores the integration of hybridization chain reaction (HCR) with silver nanoclusters (AgNCs) to form hybrid HCR‐AgNCs biosensors, highlighting advancements in their design, performance, and practical applications. It covers recent innovations, methodological improvements, and the potential of HCR‐AgNCs systems as detectors across various
Zheng Wei Wong, Siu Yee New
wiley +1 more source
Single-Molecule Nanopore Sequencing of the CpG Island from the Promoter of O6-Methylguanine-DNA Methyltransferase Provides Insights into the Mechanism of De Novo Methylation of G/C-Rich Regions. [PDF]
Sergeev AV+5 more
europepmc +1 more source
The characteristics of aptamer is most commonly represented by the dissociation constant (Kd), which is critical for aptamer optimization. Here, the assays used to evaluate Kd, including labeled and label‐free assays, are evaluated and suggestions are made to ensure that true values are obtained, while other methods are cautioned.
Stefen Stangherlin+2 more
wiley +1 more source