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Structure of Guanine Hydrochloride Dihydrate [PDF]
Nature, 1963 IN the structure determination of deoxyribonucleic acid (DNA), the method of molecular model building must be combined with that of X-ray diffraction because of the overlap and weakness of the small spacing spots on the DNA X-ray diffraction pattern1,2. For this reason, accurate knowledge of the component parts of the DNA molecule is necessary.
John Iball, H. R. Wilson
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ChemInform Abstract: PENTAAMMINERUTHENIUM-GUANINE COMPLEXES
Chemischer Informationsdienst, 1974The synthesis of several pentaammineruthenium(I1 and 111)-guanine complexes is reported, in which the metal is believed to be bound to Ni. The Ru(II1) compounds exhibit a broad low energy guanine-to-metal chargetransfer absorption, while the Ru(1I) complexes show a metal-to-ligand charge transfer in the ultraviolet.
Mike Clarke, Henry Taube
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[10] Guanine quartet structures
1992Publisher Summary Of the five nucleosides commonly found in DNA and RNA, only guanosine is capable of forming extensive self-structures in solution, hydrogen bonding with itself to give G–G base pairs, and guanine quartets. The formation of these structures was found to be uniquely dependent on monovalent cations and on the identity of the cation ...
Dipankar Sen, Walter Gilbert
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Phylogenetic Analysis and Molecular Evolution of Guanine Deaminases: From Guanine to Dendrites
Journal of Molecular Evolution, 2009Guanine deaminase (GDA; guanase) is a ubiquitous enzyme that catalyzes the first step of purine metabolism by hydrolytic deamination of guanine, resulting in the production of xanthine. This hydrolase subfamily member plays an essential role in maintaining homeostasis of cellular triphosphate nucleotides for energy, signal transduction pathways, and ...
José R. Fernández +3 more
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Reactivity of mitomycin C with synthetic polyribonucleotides containing guanine or guanine analogs
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1982The guanine residues in nucleic acids are believed to be the major covalent binding site of the antibiotic mitomycin C. To identify the specific functional group in guanine which reacts with mitomycin C, reactions were run between the antibiotic and poly(G) analogs in which guanine was blocked at the N-7 or O-6 position, or lacked the 2-amino group ...
Janet Weaver, Maria Tomasz
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ChemInform Abstract: Ozonolyses of Cytosines and Guanine.
ChemInform, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hiroshige Muramatsu +3 more
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Guanine Uptake by Human Erythrocytes
1991It has been clearly established that mature human erythrocytes cannot synthesize de novo purines (1); consequently the turnover of purine nucleotides in red cells must result from the continual entry and release of purines. Hypoxanthine and adenine uptake by human erythrocytes has been studied in our laboratories (2–4).
SPOTO, Giuseppe +2 more
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A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC)
Journal of Molecular Biology, 2001We have used CD spectroscopy, NMR spectroscopy and unrestrained molecular dynamics to study conformational properties of a DNA duplex formed by the self-complementary octamer d(GGGGCCCC). Its unusual CD spectrum contains features indicating A-like stacking of half of the bases, whereas the other half stack in a B-like fashion.
Michaela Vorlíčková +5 more
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Lipophilicity of guanine derivatives
International Journal of Pharmaceutics, 1989Abstract Lipid-water partition coefficients for acyclovir and deoxyacyclovir were determined by partition experiment. The ionisation constants and the real partition coefficients were calculated by linear regression methods. The contradiction in lipophilicity and water solubility for acyclovir and deoxyacyclovir as determined previously (Kozjek et al.
Albin Kristl +3 more
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Transglycosylation of Guanine Nucleosides
Nucleosides and Nucleotides, 1987Abstract Tetraacetylguanosine was converted into fully acetylated derivatives of acyclovir and 9-β-D-xylofuranosyl guanine in a novel transglyco-sylation ...
Jeratzy Boryski, Bozenna Golankiewicz
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