Results 131 to 140 of about 105,827 (294)

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

Pleckstrin Homology Domain-mediated Activation of the Rho-specific Guanine Nucleotide Exchange Factor Dbs by Rac1 [PDF]

, 2004
Li Cheng, Gwendolyn M. Mahon, Elena V. Kostenko, Ian P. Whitehead   +3 more
openalex   +1 more source

The Shank Family of Postsynaptic Density Proteins Interacts with and Promotes Synaptic Accumulation of the βPIX Guanine Nucleotide Exchange Factor for Rac1 and Cdc42*

Journal of Biological Chemistry, 2003
The Shank/ProSAP family of multidomain proteins is known to play an important role in organizing synaptic multiprotein complexes. Here we report a novel interaction between Shank and βPIX, a guanine nucleotide exchange factor for the Rac1 and Cdc42 small
Eunhye Park, M. Na, Jeonghoon Choi, Seho Kim, Jae-Ran Lee, Jiyoung Yoon, Dongeun Park, M. Sheng, Eunjoon Kim   +8 more
semanticscholar   +1 more source

Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence

iScience
Summary: The development of antifungal drugs requires novel molecular targets due to limited treatment options and drug resistance. Through chemical screening and establishment of a novel genetic technique to repress gene expression in Trichophyton ...
Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata   +5 more
doaj   +1 more source

Identification of a tight junction–associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability [PDF]

, 2003
Gaëlle Benais-Pont, Anu Punn, Catalina Flores-Maldonado, Judith J. Eckert, Graça Raposo, Tom P. Fleming, Marcelino Cereijido, María S. Balda, Karl Matter   +8 more
openalex   +1 more source

Polar‐localized EXO70G1 regulates root development in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
The putative exocyst subunit EXO70G1 exhibits apical‐basal polarity in Arabidopsis root cells; this polarity stabilizes membrane domains to facilitate targeting of the auxin transporter PIN‐FORMED2 during root development. ABSTRACT Cellular asymmetry, which represents a fundamental characteristic of cell polarity, is prominently illustrated by the ...
Juan Li, Zhendong Liu, Lixue Gong, Shuju Zhao, Qing Lu, Shan Gao, Su Jiang, Xiaonan Liu, Long Ma, Guangyou Duan, Dayong Cui, Shipeng Li   +11 more
wiley   +1 more source

Trichoderma genome and multiomics insight into promoting yield and reducing grain cadmium in barley and wheat

Journal of Integrative Plant Biology, EarlyView.
Summary: The fungal strain Trichoderma nigricans T32781 improved yield and reduced the grain cadmium concentrations of wheat and barley in cadmium‐polluted soils through microbial and metabolic interactions, offering a potential strategy for enhancing crop productivity and food safety in cadmium‐contaminated fields.
Shuo Zhang, Cheng‐Wei Qiu, Shou‐Heng Shi, Jakkrit Sreesaeng, Zi‐Feng Gao, Chulong Zhang, Weihua Mao, Mohamed Abdelalim Ali, Zhong‐Hua Chen, Feibo Wu   +9 more
wiley   +1 more source

Interaction of GRASP, a Protein encoded by a Novel Retinoic Acid-induced Gene, with Members of the Cytohesin Family of Guanine Nucleotide Exchange Factors [PDF]

, 2000
Daniel J. Nevrivy, Valerie J. Peterson, Dorina Avram, Jane E. Ishmael, Scott G. Hansen, Paul Dowell, Dennis E. Hruby, Marcia I. Dawson, Mark Leid   +8 more
openalex   +1 more source

Gz, a guanine nucleotide-binding protein with unique biochemical properties [PDF]

, 1990
Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific antisera to identify the protein in tissues and to assay it ...
Casey, Patrick J., Fong, Henry K. W., Gilman, Alfred G., Simon, Melvin I.   +3 more
core  

Use of high throughput sequencing to observe genome dynamics at a single cell level

, 2009
With the development of high throughput sequencing technology, it becomes possible to directly analyze mutation distribution in a genome-wide fashion, dissociating mutation rate measurements from the traditional underlying assumptions. Here, we sequenced
A. Soldatov, Bentley, Benzer, Bhanot, Cai, Cairns, Cox, Cupples, D. Parkhomchuk, Dotsch, Elowitz, Foster, Foster, Gabriel, Goodarzi, Hall, Hill-Perkins, Lindahl, Loechler, Loveless, Meselson, Mitra, Niki, Raser, Rosche, Sedgwick, Singer, V. Amstislavskiy, V. Ogryzko, Yu   +29 more
core   +1 more source