Results 161 to 170 of about 105,827 (294)

Rho Guanine Nucleotide Exchange Factor 10

Definitions, 2020

semanticscholar   +1 more source

Classical and emergent insulin signaling dual changes in type 2 diabetes revealed by human iPSC‐derived hepatocytes

Journal of Diabetes Investigation, EarlyView.
Shiyin Zheng, Xiaona Cui, Rui Wei, Tianpei Hong   +3 more
wiley   +1 more source

Altered Inflammatory Signature in a C9ORF72 ‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, Volume 74, Issue 1, January 2026.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source

Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code. [PDF]

J Biol Chem, 2023
Herrmann E, Langemeyer L, Auffarth K, Ungermann C, Kümmel D.   +4 more
europepmc   +1 more source

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis [PDF]

, 2013
Mélanie Laurin, Jennifer Huber, Ariane Pelletier, Tarek Houalla, Morag Park, Yoshinori Fukui, Benjamin Haibe‐Kains, William J. Muller, Jean‐François Côté   +8 more
openalex   +1 more source

Gαs defines the fundamental coupling mechanism of insulin secretion

Journal of Diabetes Investigation, EarlyView.
Jun Shirakawa
wiley   +1 more source

Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Eli C. Olson, Adam Williams, Stephanie C. Eisenbarth   +2 more
wiley   +1 more source

Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms. [PDF]

Cell Commun Signal, 2023
Rodríguez-Blázquez A, Carabias A, Morán-Vaquero A, de Cima S, Luque-Ortega JR, Alfonso C, Schuck P, Manso JA, Macedo-Ribeiro S, Guerrero C, de Pereda JM.   +10 more
europepmc   +1 more source

Rho Guanine Nucleotide Exchange Factor 12

Definitions, 2020

semanticscholar   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, Volume 15, Issue 12, Page 1918-1929, December 2025.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source