Results 171 to 180 of about 105,827 (294)
The guanine nucleotide exchange factor Vav3 intervenes in the migration pathway of oligodendrocyte precursor cells on tenascin-C. [PDF]
Schäfer I +6 more
europepmc +1 more source
ABSTRACT Metastasis is the leading cause of death related to breast cancer. Premetastatic niches (PMNs), which are remodelled by the primary tumours in distant organs, are essential for the colonisation of disseminated cancer cells. The vascular niche is among the most pivotal PMNs in breast cancer lung metastasis, and the underlying mechanism remains ...
Xu Li +8 more
wiley +1 more source
Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes. [PDF]
Nishikawa M +4 more
europepmc +1 more source
Structure and Function of Heterotrimeric G Protein-Regulated Rho Guanine Nucleotide Exchange Factors [PDF]
Mohamed Aittaleb +2 more
openalex +1 more source
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
This paper describe a 3‐year‐old girl with Turner syndrome who presented with recurrent cough and dyspnea and was diagnosed with hereditary PAP. Genetic analysis revealed a novel hemizygous mutation in the CSF2RA gene (NM_000402.4:c.200_204del, p.Asn67SerfsTer8), which was confirmed as a de novo pathogenic variant and had not been reported previously ...
Qiang Chen +6 more
wiley +1 more source
Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling [PDF]
Shuichi Furuta +5 more
openalex +1 more source
Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan +7 more
wiley +1 more source

