Results 191 to 200 of about 84,425 (312)
ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay
ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński +2 more
wiley +1 more source
ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno +5 more
wiley +1 more source
Genetic Diversity and Phylogenetic Relationships of Mosquitoes (Diptera: Culicidae) in Central Nepal
This study presents a molecular survey of mosquitoes in central Nepal, analyzing 18 species across eight genera using mitochondrial COI sequencing. The results revealed significant genetic divergence, clarify phylogenetic relationships, and confirm the presence of newly recorded species, including Aedes japonicus, Anopheles farauti, and Culex sasai ...
Punya Ram Sukupayo +4 more
wiley +1 more source
The Genetic Basis of Color Polymorphism in the Orb‐Web Spider Gasteracantha cancriformis
This study investigates the genetic basis of coloration in the polymorphic spider Gasteracantha cancriformis using RNA‐seq data from different female color morphs. We assembled a reference transcriptome and identified differentially expressed genes associated with known pigmentation pathways, including carotenoids, melanin, ommochromes, and pteridines.
Paula Torres‐Quintero +3 more
wiley +1 more source
Reduced Dietary Protein Induces Changes in the Dental Proteome
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs +2 more
wiley +1 more source
Targeting guanine nucleotide exchange factors for novel cancer drug discovery. [PDF]
Bannoura SF +5 more
europepmc +1 more source
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
New Mechanisms Underlying Oncogenesis in Dbl Family Rho Guanine Nucleotide Exchange Factors. [PDF]
Ravala SK, Tesmer JJG.
europepmc +1 more source

