Results 191 to 200 of about 83,277 (241)

Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors. [PDF]

J Biol Chem, 2013
Oner SS, Maher EM, Gabay M, Tall GG, Blumer JB, Lanier SM.   +5 more
europepmc   +1 more source

Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.

J Cell Sci, 2016
Zhou W, Li X, Premont RT.
europepmc   +1 more source

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. [PDF]

Oncogene, 2014
Cook DR, Rossman KL, Der CJ.
europepmc   +1 more source

Disrupting the KRAS-SOS1 protein-protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy. [PDF]

Front Chem
Kamel EM, Khadrawy SM, Ali MAM, Abukhadra MR, Yassin NYS, Alkhedhairi S, Aba Alkhayl FF, Lamsabhi AM.   +7 more
europepmc   +1 more source

The Guanine Exchange Factor <i>SsEFA6</i> Participates in Appressorium Formation and Virulence in <i>Sclerotinia sclerotiorum</i>. [PDF]

J Fungi (Basel)
Wang K, Wang T, Xia Q, Xie N, Cao J, Xia S.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Dbl family guanine nucleotide exchange factors

Trends in Biochemical Sciences, 2001
The Dbl family of guanine nucleotide exchange factors are multifunctional molecules that transduce diverse intracellular signals leading to the activation of Rho GTPases. The tandem Dbl-homology and pleckstrin-homology domains shared by all members of this family represent the structural module responsible for catalyzing the GDP-GTP exchange reaction ...
Yi Zheng
openaire   +4 more sources

The guanine nucleotide-exchange factor, eIF-2B

Biochimie, 1994
Eukaryotic initiation factor eIF-2B catalyses the exchange of guanine nucleotides on another translation initiation factor, eIF-2, which itself mediates the binding of the initiator Met-tRNA to the 40S ribosomal subunit during translation initiation. eIF-2B promotes the release of GDP from inactive [eIF-2.GDP] complexes, thus allowing formation of the ...
N, Price, C, Proud
openaire   +2 more sources

A Small Molecule-Regulated Guanine Nucleotide Exchange Factor

Journal of the American Chemical Society, 2009
Selective, pharmacological agents are attractive tools for studying signal transduction because they allow rapid, reversible, and dose-dependent control over intracellular protein function. However, for many targets the identification of potent and selective small molecule agonists and antagonists is a formidable challenge.
Inna, Goreshnik, Dustin J, Maly
openaire   +2 more sources

Guanine nucleotide exchange factors: Activators of Ras superfamily proteins

Molecular Reproduction and Development, 1995
AbstractMembers of the Ras superfamily of proteins function as regulated GDP/GTP switches that cycle between active GTP‐complexed and inactive GDP‐complexed states. Guanine nucleotide exchange factors (GEFs) stimulate formation of the GTP‐bound state, whereas GTPase activating proteins (GAPs) catalyze the formation of the GDP‐bound state.
A F, Overbeck, T R, Brtva, A D, Cox, S M, Graham, S Y, Huff, R, Khosravi-Far, L A, Quilliam, P A, Solski, C J, Der   +8 more
openaire   +2 more sources