Results 71 to 80 of about 9,354,840 (235)
Coordinating the Activation of RhoA by Diverse RhoGEFs: SmgGDS and G-alpha-q-Responsive Dbl Family Guanine Nucleotide Exchange Factors [PDF]
, 2007 G proteins are molecular switches that fluctuate between on and off states and regulate a multitude of essential signaling cascades within the cell. G proteins implicated in signal transduction can be divided into two major groups, the heterotrimeric G ...
Rojas, Rafael Jose
core +1 more source
Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption
Advanced Science, EarlyView.This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu +7 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
PLoS ONE, 2007 Small G proteins of the Arf and Rab families are fundamental to the organisation and activity of intracellular membranes. One of the most well characterised of these G proteins is mammalian Arf6, a protein that participates in many cellular processes ...
Alison K Gillingham, Sean Munro
doaj +1 more source
A non-linear system patterns Rab5 GTPase on the membrane
eLife, 2020 Proteins can self-organize into spatial patterns via non-linear dynamic interactions on cellular membranes. Modelling and simulations have shown that small GTPases can generate patterns by coupling guanine nucleotide exchange factors (GEF) to effectors ...
Alice Cezanne +4 more
doaj +1 more source
The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms [PDF]
, 2008 © 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Sakwa, I, Höfken, T, Just, U, Tiedje, C
core +1 more source
Advanced Science, EarlyView.Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao +6 more
wiley +1 more source
Analysis of Rho GTPase signalling pathways regulating epithelial morphogenesis [PDF]
, 2010 Rho GTPases are molecular switches controlling many aspects of cell behaviour, including cell cycle progression, cell division, migration and morphology. The activity of Rho proteins is regulated by conformational changes induced by binding of guanine
Wallace, S.
core
Localization of the translational guanine nucleotide exchange factor eIF2B: A common theme for GEFs?
, 2006 The eukaryotic initiation factor 2B (eIF2B) serves an essential recycling function in protein synthesis. As the guanine nucleotide exchange factor for eIF2, it recycles eIF2 from a GDP to a GTP bound form that is competent for translation initiation ...
Mark P. Ashe +4 more
core +1 more source
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source