Results 211 to 220 of about 150,931 (301)

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, EarlyView.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

i-motifs: DNA structures with regulatory functions and therapeutic potential. [PDF]

Einstein (Sao Paulo)
Aguiar MP, Gomes ESB, Vieira JF.
europepmc   +1 more source

Determination of Nucleotide-Nucleotide and Nucleotide-Amino Acid Binding Interactions from All-Atom Potential-of-Mean-Force Calculations. [PDF]

ACS Phys Chem Au
Feito A, Pedraza E, Cuesta E, Castro A, Rey A, Sanchez-Burgos I, Collepardo-Guevara R, Tejedor AR, Espinosa JR.   +8 more
europepmc   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Site-specific ribozyme-mediated alkylation of DNA substrates. [PDF]

Nucleic Acids Res
He Y, Wilson TJ, Deng J, Luo Y, Yan K, Xie Y, Lilley DMJ, Huang L.   +7 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

1-Deazainosine-impact on RNA structure and role in exploring ribozyme catalysis. [PDF]

Chem Sci
Mitteregger C, Bereiter R, Schramm A, Ennifar E, Kreutz C, Micura R.   +5 more
europepmc   +1 more source

Dynamic Surface‐Enhanced Raman Scattering Platform With Multiscale Nanostructural Engineering and Programmable Surface Energy for Artificial Intelligence‐Assisted Discrimination of Helicobacter pylori

Advanced Oncology, Volume 1, Issue 1, December 2026.
This study develops a dynamic surface‐enhanced Raman scattering (D‐SERS) platform integrating multiscale nanoparticle geometry, quantum dot coupling, surface‐energy programming, and a multilayer perceptron model for AI‐assisted classification. It enables ultrahigh sensitivity, noninvasive detection, and specific Helicobacter pylori identification.
Ming‐Chang Lu, Chia‐Jung Lee, Chih‐Yuan Yao, Bo‐Ying Wu, Chih‐Wei Chiu   +4 more
wiley   +1 more source

Kiss and spit metabolomics highlight the role of host purine metabolism during pathogen infection. [PDF]

mSphere
Gallego-Lopez GM, Olson WJ, Tibabuzo-Perdomo AM, Stevenson D, Amador-Noguez D, Lawrence G, Leahy JW, Contreras Guzman E, Skala MC, Knoll LJ.   +9 more
europepmc   +1 more source

Minimally processed, human‐grade diet alters canine epigenetic ageing: Results from a pilot study

Veterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks have emerged as accurate tools for assessing biological ageing and evaluating dietary and lifestyle interventions in humans and mice.
Aimee Chen, Wei Guo, Janina A. Krumbeck, Dan Su, Vincent Michels, Xiaojing Yang   +5 more
wiley   +1 more source