Results 291 to 300 of about 103,400 (342)
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Receptor‐stimulated guanine‐nucleotide‐triphosphate binding to guanine‐nucleotide‐binding regulatory proteins

European Journal of Biochemistry, 1994
In order to study whether phosphate transfer reactions are involved in the binding of guanine nucleotide triphosphates to guanine‐nucleotide‐binding regulatory proteins, binding of the GTP analogues, guanosine 5′‐[γ‐thio]triphosphate, GTP[S], and guanosine 5′‐[β,γ‐imino]triphosphate, p[NH]ppG, and the regulation of binding by the formly‐peptide ...
S, Kaldenberg-Stasch   +4 more
openaire   +2 more sources

Guanine Nucleotide Dissociation Stimulators

1993
Small Ras-like GTPases function as bipolar molecular switches to control a variety of cellular processes (Bourne et al. 1991a,b). The switches cycle between GTP- and GDP-bound states. Evidence from oncogenic mutants of Ras identified the GTP-bound form as the active state, a conclusion that has been substantiated by the effects of dominant negative ...
I. G. Macara, E. S. Burstein
openaire   +1 more source

Dbl family guanine nucleotide exchange factors

Trends in Biochemical Sciences, 2001
The Dbl family of guanine nucleotide exchange factors are multifunctional molecules that transduce diverse intracellular signals leading to the activation of Rho GTPases. The tandem Dbl-homology and pleckstrin-homology domains shared by all members of this family represent the structural module responsible for catalyzing the GDP-GTP exchange reaction ...
openaire   +2 more sources

Guanine-Nucleotide-Binding Regulatory Proteins

1985
Studies of the hormone-sensitive adenylate cyclase complex and of mechanisms of transduction of visual information have led to the discovery of a family of guanine-nucleotide-binding regulatory proteins. This family is now known to include at least four highly homologous members.
Alfred G. Gilman   +3 more
openaire   +1 more source

Differential regulation of the α2-adrenergic receptor by Na+ and guanine nucleotides

Nature, 1980
Thomas Michel   +2 more
exaly  

Capturing cyclic nucleotides in action: snapshots from crystallographic studies

Nature Reviews Molecular Cell Biology, 2007
Johannes L Bos
exaly  

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

Nature Reviews Molecular Cell Biology, 2005
Channing J Der, John E Sondek
exaly  

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