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The Guanine Nucleotide-Binding Switch in Three Dimensions
Science, 2001Guanine nucleotide–binding proteins regulate a variety of processes, including sensual perception, protein synthesis, various transport processes, and cell growth and differentiation. They act as molecular switches and timers that cycle between inactive guanosine diphosphate (GDP)–bound and active guanosine triphosphate (GTP)–bound states.
I R, Vetter, A, Wittinghofer
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Transducin: A Signaling Switch Regulated by Guanine Nucleotides
1989Publisher Summary This chapter discusses the information obtained from the biochemical studies of transducin and attempts to integrate this information with the proposed structure of the GTP binding α subunit of transducin (T α ). One of the best-studied biological processes regulated by G proteins is the visual excitation of vertebrate ...
Y K, Ho +3 more
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Dbl family guanine nucleotide exchange factors
Trends in Biochemical Sciences, 2001The Dbl family of guanine nucleotide exchange factors are multifunctional molecules that transduce diverse intracellular signals leading to the activation of Rho GTPases. The tandem Dbl-homology and pleckstrin-homology domains shared by all members of this family represent the structural module responsible for catalyzing the GDP-GTP exchange reaction ...
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Guanine nucleotides in protein synthesis
Archives of Biochemistry and Biophysics, 1974Ernest Hamel, Michael Cashel
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Characterisation of the interaction of guanine nucleotides with ribosomal GTPase Lsg1
Biochimica Et Biophysica Acta - Proteins and Proteomics, 2021Núria Sanchez Puig
exaly
Chemiluminescence determination of guanine and its nucleosides and nucleotides using phenylglyoxal
Analytica Chimica Acta, 1994Masaaki Kai
exaly
Guanine nucleotides decrease the affinity of substance P binding to its receptor
European Journal of Pharmacology, 1990Arti Patel, Norman D Boyd, N D Boyd
exaly

