Results 271 to 280 of about 52,163 (306)
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A guanine nucleotide-binding protein in human astrocytoma
Neurological Research, 1990We compared, by immunoblotting and immunohistochemical staining, the distribution of the alpha subunit of Go in human normal brain tissue with that in human brain tumours of neuroectodermal origin. The ten tumour samples included seven high-grade astrocytomas (grades III and IV) and three low-grade astrocytomas (grade II).
K, Takenaka +7 more
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Effect of guanine nucleotides on the hydrophobic interaction of tubulin
Biochemistry, 1990The influence of guanine nucleotides on the binding of tubulin to hydrophobic components is investigated. Tubulin binds to a hydrophobic phenyl-Sepharose gel in a reversible, nucleotide-dependent way. Assembly-competent tubulin is released with ion-free water as eluent. It contains one guanosine triphosphate per dimer.
I, Hanssens, J, Baert, F, Van Cauwelaert
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A function of huntingtin in guanine nucleotide exchange on Rab11
NeuroReport, 2008Huntingtin is ubiquitously expressed and enriched in the brain. Deletion of the huntingtin gene in mice is lethal during early embryonic development. The function of huntingtin is, however, not clear. Here, we report that huntingtin is important for the function of Rab11, a critical GTPase in regulating membrane traffic from recycling endosomes to the ...
Xueyi, Li +11 more
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Guanine Nucleotide Dissociation Stimulators
1993Small Ras-like GTPases function as bipolar molecular switches to control a variety of cellular processes (Bourne et al. 1991a,b). The switches cycle between GTP- and GDP-bound states. Evidence from oncogenic mutants of Ras identified the GTP-bound form as the active state, a conclusion that has been substantiated by the effects of dominant negative ...
I. G. Macara, E. S. Burstein
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Dbl family guanine nucleotide exchange factors
Trends in Biochemical Sciences, 2001The Dbl family of guanine nucleotide exchange factors are multifunctional molecules that transduce diverse intracellular signals leading to the activation of Rho GTPases. The tandem Dbl-homology and pleckstrin-homology domains shared by all members of this family represent the structural module responsible for catalyzing the GDP-GTP exchange reaction ...
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Guanine Nucleotide Binding Proteins and Signal Transduction
1988Publisher Summary This chapter discusses the general aspects and functions of guanine nucleotide binding proteins and signal transduction. The function of several identified G-proteins such as G o and the multiple forms of “G i ” are also defined. The function of ras and ras -related gene products likewise are also elucidated in the chapter.
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Guanine nucleotides in protein synthesis
Archives of Biochemistry and Biophysics, 1974Ernest Hamel, Michael Cashel
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Chemiluminescence determination of guanine and its nucleosides and nucleotides using phenylglyoxal
Analytica Chimica Acta, 1994Masaaki Kai
exaly
Effects of guanine nucleotides on cns neuropeptide receptors
Journal of Supramolecular Structure and Cellular Biochemistry, 1981Terry W Moody
exaly