Results 131 to 140 of about 201,939 (380)
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
Enzymic Synthesis of Xanthosine- and Guanosine-5-phosphate from Inosine-5-phosphate. [PDF]
, 1955 Ulf Lagerkvist +3 more
openalex +1 more source
Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 1972 Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core +1 more source
Methods for Controlling Small GTPase Activity
ChemBioChem, EarlyView.This concept highlights recent and emerging methods for controlling small GTPase activity, encompassing both small‐molecule‐based approaches and protein engineering strategies. The use of these approaches to advance the understanding of small GTPase function, current limitations, and future outlook is discussed.
Benjamin Faulkner +3 more
wiley +1 more source
The Link between Purine Metabolism and Production of Antibiotics in Streptomyces
Antibiotics, 2019 Stress and starvation causes bacterial cells to activate the stringent response. This results in down-regulation of energy-requiring processes related to growth, as well as an upregulation of genes associated with survival and stress responses. Guanosine
Smitha Sivapragasam, Anne Grove
doaj +1 more source
Guanosine di- and tri-phosphates in the phosphate metabolism of cerebral tissues promoted by electrical pulses [PDF]
, 1957 P. J. Heald
openalex +1 more source
Cyclic guanosine monophosphate as a mediator of vasodilation.
Journal of Clinical Investigation, 1986 Although cyclic guanosine monophosphate (GMP)' was first described in biological samples more than two decades ago, its role in some physiological processes has only become apparent in the past few years (see references 1-4).
F. Murad
semanticscholar +1 more source
Synthesis of Nucleoside Derivatives by Biomimetic Ester Migration
ChemBioChem, EarlyView.In tRNA aminoacylated nucleosides represent the central transfer unit of amino acids. An occurring 2′‐3′‐transaminoacylation is biomimetically exploited to successfully synthesize nucleosidic acid esters. This approach can be further expanded on sulfonic acid esters, which has the potential of a broad range of stereo‐ and regio‐controlled modifications
Nathalie J. Kurrle +8 more
wiley +1 more source
Inability of Guanosine to Act as a Precursor of Polynucleotides. [PDF]
, 1950 E. Hammarsten +3 more
openalex +1 more source