Results 131 to 140 of about 194,604 (252)

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands

open access: yesCell Reports, 2018
Summary: Toll-like receptor 7 (TLR7) is an innate immune receptor for single-stranded RNA (ssRNA) and has important roles in infectious diseases. We previously reported that TLR7 shows synergistic activation in response to two ligands, guanosine and ...
Zhikuan Zhang   +10 more
doaj  

Guanosine and its role in neuropathologies

open access: yesPurinergic Signalling Purinergic Signalling, 2016
L. Bettio, J. Gil-Mohapel, A. Rodrigues
semanticscholar   +1 more source

Liquid chromatographic method for extracellular Guanosine 5′-triphosphate and tetrahydrobiopterin pathway products analysis from cadaveric samples and human biofluids

open access: yesJournal of Chromatography Open
To gain a deep insight and to obtain a superior understanding about guanosine-based pathway, this paper reports an innovative approach to study this critical subject.
M. Perrucci   +8 more
doaj  

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