Results 151 to 160 of about 266,483 (401)

The role of DNA and RNA guanosine oxidation in cardiovascular diseases

Pharmacological Research
Cardiovascular diseases (CVD) persist as a prominent cause of mortality worldwide, with oxidative stress constituting a pivotal contributory element. The oxidative modification of guanosine, specifically 8-oxoguanine, has emerged as a crucial biomarker ...
Yiping Li, Xiaolong Wang
doaj   +1 more source

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways

Purinergic Signalling Purinergic Signalling, 2019
T. Dal-Cim, G. G. Poluceno, D. Lanznaster, K. A. de Oliveira, C. B. Nedel, C. Tasca   +5 more
semanticscholar   +1 more source

Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro

ChemistryEurope, EarlyView.
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling, Wiebke Teich, Bayram Terzi, Helena Schepers, Sabine Hüwel, Andrea Rentmeister   +5 more
wiley   +1 more source

Biosynthesis of Guanosine 5'-Phosphate

, 1958
Ulf Lagerkvist
openalex   +1 more source

Production of Guanosine-5′-Monophosphate and Inosine-5′-Monophosphate by Fermentation [PDF]

, 1966
A. L. Demain, M. Jackson, Ronald A. Vitali, David Hendlin, Theodore A. Jacob   +4 more
openalex   +1 more source

The Senegalese Sole Mx gene promoter contains a variable microsatellite region involved in the transcriptional [PDF]

, 2015
Interferons (IFNs) play a key role against viral infections by stimulating the expression of IFN stimulated genes, such as Mx. The transcriptional regulation of these genes in fish are poorly understood.
Alonso-Sanchez, Maria del Carmen, Bejar-Alvarado, Julia, García-Rosado, Esther, Vieytes, Lisandro P, Álvarez-Torres, Daniel   +4 more
core  

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

eLife
Cyclic nucleotide binding domains (CNB) confer allosteric regulation by cAMP or cGMP to many signaling proteins, including PKA and PKG. PKA of phylogenetically distant Trypanosoma is the first exception as it is cyclic nucleotide-independent and ...
Veronica Teresa Ober, George Boniface Githure, Yuri Volpato Santos, Sidney Becker, Gabriel Moya Munoz, Jérôme Basquin, Frank Schwede, Esben Lorentzen, Michael Boshart   +8 more
doaj   +1 more source

Identification of guanosine triphosphate as the 5'-terminus of RNA from bacteriophage Q-beta and R23. [PDF]

, 1968
M. Watanabe, J. T. August
openalex   +1 more source

Phylogeny of conserved adenines in linkers of Group-I introns [PDF]

, 2009
We have analyzed the linkers in group-I introns, a characteristic region that is crucial to the folding and splicing process of the folded RNA, in seventy sequences spreading across r-RNA, t-RNA and organelle genes from various organisms including algae,
Chandrasekhar Kesavan, Natarajan Ganesan
core   +1 more source