Results 11 to 20 of about 266,483 (401)
On the epigenetic role of guanosine oxidation
Redox Biology, 2020 Chemical modifications of DNA and RNA regulate genome functions or trigger mutagenesis resulting in aging or cancer. Oxidations of macromolecules, including DNA, are common reactions in biological systems and often part of regulatory circuits rather than
Marco Giorgio +4 more
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Guanosine and its role in neuropathologies [PDF]
Purinergic Signalling, 2016 Guanosine is a purine nucleoside thought to have neuroprotective properties. It is released in the brain under physiological conditions and even more during pathological events, reducing neuroinflammation, oxidative stress, and excitotoxicity, as well as exerting trophic effects in neuronal and glial cells.
L. Bettio, J. Gil-Mohapel, A. Rodrigues
semanticscholar +4 more sources
Frontiers in Pharmacology, 2018 The extracellular guanosine 5′-triphosphate, GTP, has been demonstrated to be an enhancer of myogenic cell differentiation in a murine cell line, not yet in human muscle cells.
Tiziana Pietrangelo +9 more
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Molecules, 2013 In the past 30 years, only three natural products have been sources of new drugs with antiplatelet activity. In this study, we have demonstrated for the first time that guanosine from Solanum lycopersicum possesses antiplatelet (secretion, spreading ...
Iván Palomo +5 more
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The potential therapeutic effect of guanosine after cortical focal ischemia in rats.
PLoS ONE, 2014 Background and purposeStroke is a devastating disease. Both excitotoxicity and oxidative stress play important roles in ischemic brain injury, along with harmful impacts on ischemic cerebral tissue. As guanosine plays an important neuroprotective role in
Gisele Hansel +7 more
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The Isolation of Guanosine Tetraphosphate from Commercially Available Preparations of Guanosine Triphosphate [PDF]
Journal of Biological Chemistry, 1965 Jared Gardner, Mahlon B. Hoagland
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Electrocatalytic Oxidation of Guanine, Guanosine, and Guanosine Monophosphate [PDF]
Biophysical Journal, 2007 The electrochemical behavior of guanine, guanosine, and guanosine monophosphate (GMP) at redox polymer film modified indium tin oxide electrodes is examined by voltammetry and redox titration. Utilizing the redox polymer-coated electrodes as indicator electrodes, a new method for measuring the oxidation potentials, based on monitoring their catalytic ...
Xie, H., Yang, D., Heller, A., Gao, Z.
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GUANOSINE DIPHOSPHATE MANNOSE [PDF]
Journal of Biological Chemistry, 1954 Blanco y ...
Cabib, Enrico, Leloir, Luis Federico
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Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets. [PDF]
Journal of Clinical Investigation, 1998 We isolated and identified nucleoside(5') oligophospho-(5') nucleosides containing adenosine and guanosine (ApnG; n = 3-6) as well as diguanosine polyphosphates (GpnG; n = 3-6) in human platelets. For identification, UV spectrometry, matrix-assisted laser desorption/ionization, postsource decay matrix-assisted laser desorption/ionization mass ...
Martin Tepel +10 more
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