Results 21 to 30 of about 231,754 (311)

Guanosine Protects Neuronal PC12 Cells from Serum Deprivation-induced Cell Death

Pteridines, 2012
Survival of neurons is dependent on the presence of trophic and non-trophic factors. Previous findings showed that purine nucleosides have the potential to rescue cells from hypoxia-induced cell death. Here we demonstrate that purine nucleoside guanosine
Thauerer Bettina, Baeumer Bastian E., Fellner Lisa, Kuzdas Daniela, Ramberger Melanie, Baier-Bitterlich Gabriele   +5 more
doaj   +1 more source

Dynamics of Microtubule Growth and Catastrophe [PDF]

, 2007
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii ...
Antal, T., Chakraborty, B., Krapivsky, P. L., Mailman, M., Redner, S.   +4 more
core   +1 more source

Modulation of phenylalanine and tyrosine concentrations by ischemia and guanosine in neuronal PC12 cells

Pteridines, 2013
Survival of neurons is dependent on the presence of trophic and non-trophic factors. We have previously observed the protective capacity of purine nucleosides in hypoxic neuronal cell cultures.
Thauerer Bettina, Geisler Simon, Fuchs Dietmar, Baier-Bitterlich Gabriele   +3 more
doaj   +1 more source

Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets. [PDF]

Journal of Clinical Investigation, 1998
We isolated and identified nucleoside(5') oligophospho-(5') nucleosides containing adenosine and guanosine (ApnG; n = 3-6) as well as diguanosine polyphosphates (GpnG; n = 3-6) in human platelets. For identification, UV spectrometry, matrix-assisted laser desorption/ionization, postsource decay matrix-assisted laser desorption/ionization mass ...
H, Schlüter, I, Grobeta, J, Bachmann, R, Kaufmann, M, van der Giet, M, Tepel, J R, Nofer, G, Assmann, M, Karas, J, Jankowski, W, Zidek   +10 more
openaire   +2 more sources

Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]

, 1975
Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Inaba, Kozo, Oda, Takuzo
core   +1 more source

Construction of Supramolecular Organogel with Circularly Polarized Luminescence by Self-Assembled Guanosine Octamer

Cell Reports Physical Science, 2020
Summary: Gel formation using guanosine self-assembly is an important process in supramolecular chemistry. Here, we report the stepwise construction of circularly polarized luminescent supramolecular organogels from self-assembled guanosine quadruplexes ...
Yanbin Zhang, Ying He, Lukasz Wojtas, Xiaodong Shi, Hao Guo   +4 more
doaj   +1 more source

A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]

, 1988
A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman, A.R. Ashton, C. foyer, C. Schindler, C.V.C. Glover, D.J. Arnon, F.A. Ventimiglia, G.E. Lienhard, G.M. Hathaway, G.M. Hathaway, G.M. Hathaway, H. Erdmann, H. Hidaka, J. Joyard, J. Soll, J. Soll, J. Soll, J. Soll, J.F. Allen, J.F. Kuo, J.G. Chafouleas, K. Birkenhead, K. Cline, K. Keegstra, P. Bhalla, R. Ranjeva, R.A. Douce, R.J.H. Budde, S. Gowda, S. Murakami, S.J. Coughlan, T.F.J. Yan, U.K. Laemmli, W.A. Laing, Z.F. Lin   +34 more
core   +1 more source

In Silico and In Vitro Screening of Antipathogenic Properties of Melianthus comosus (Vahl) against Pseudomonas aeruginosa

Antibiotics, 2021
Bacterial quorum sensing (QS) system regulates pathogenesis, virulence, and biofilm formation, and together they contribute to nosocomial infections. Opportunistic pathogens, such as Pseudomonas aeruginosa, rely on QS for regulating virulence factors ...
Itumeleng T. Baloyi, Idowu J. Adeosun, Abdullahi A. Yusuf, Sekelwa Cosa   +3 more
doaj   +1 more source

Synthetic (p)ppGpp analogue is an inhibitor of stringent response in mycobacteria [PDF]

, 2017
Bacteria elicit an adaptive response against hostile conditions such as starvation and other kinds of stresses. Their ability to survive such conditions depends, in part, on stringent response pathways.
Bhardwaj, Neerupma, Chatterji, Dipankar, Flentie, Kelly, Jayaraman, Narayanaswamy, Maiti, Krishnagopal, Stallings, Christina L, Syal, Kirtimaan   +6 more
core   +2 more sources

Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice. [PDF]

PLoS ONE, 2015
Metabolic homeostasis is critical for all biological processes in the brain. The metabolites are considered the best indicators of cell states and their rapid fluxes are extremely sensitive to cellular changes.
Xi Chen, Chengsong Xie, Lixin Sun, Jinhui Ding, Huaibin Cai   +4 more
doaj   +1 more source