Results 221 to 230 of about 266,483 (401)

Guanosine inhibits LPS-induced pro-inflammatory response and oxidative stress in hippocampal astrocytes through the heme oxygenase-1 pathway

open access: yesPurinergic Signalling Purinergic Signalling, 2015
Bruna Bellaver   +5 more
semanticscholar   +1 more source

Hypoxia Triggers ALYREF‐Mediated m5C Methylation of KIF20A to Activate KIF20A/BUB1 for Generating Ferroptosis Resistance in Cervical Cancer Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ferroptosis resistance is a key player in cervical cancer (CC) development. Hypoxia is a negative factor affecting CC treatment by inducing ferroptosis resistance. Our study aimed to investigate the detailed mechanisms of hypoxia‐induced ferroptosis resistance in CC cells.
Yan Gao, Ting Zou
wiley   +1 more source

Methylglyoxal-induced RNA modifications decrease RNA stability and translation and are associated with type 2 diabetes. [PDF]

open access: yesMol Metab
Lopez Gonzalez EJ   +10 more
europepmc   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Guanine Crystal Formation at Physiological pH. [PDF]

open access: yesCryst Growth Des
Tah Roy B   +8 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

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