Results 21 to 30 of about 266,483 (401)
FEBS Letters, 1984 Bovine serum albumin conjugates of guanosine prepared by the periodate method was used as immunogen to elicit guanosine antibodies in rabbits. The specificities of the antibodies were studied by the inhibition of their binding to [3H]Gox‐red, [32P]DNA and [3H]RNA by related non‐radioactive compounds.
Iswari, S, Jacob, TM
openaire +3 more sources
Impact of C-Terminal Chemistry on Self-Assembled Morphology of Guanosine Containing Nucleopeptides
Molecules, 2020 Herein, we report the design and characterization of guanosine-containing self-assembling nucleopeptides that form nanosheets and nanofibers. Through spectroscopy and microscopy analysis, we propose that the peptide component of the nucleopeptide drives ...
Katherine Boback +5 more
doaj +1 more source
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
, 2012 Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz +60 more
core +2 more sources
Neuromodulatory Effects of Guanine-Based Purines in Health and Disease
Frontiers in Cellular Neuroscience, 2018 The function of guanine-based purines (GBPs) is mostly attributed to the intracellular modulation of heteromeric and monomeric G proteins. However, extracellular effects of guanine derivatives have also been recognized.
Carla I. Tasca +9 more
doaj +1 more source
Biosensors, 2023 Chemiluminescence is widely used for hydrogen peroxide detection, mainly exploiting the highly sensitive peroxidase-luminol-H2O2 system. Hydrogen peroxide plays an important role in several physiological and pathological processes and is produced by ...
Donato Calabria +8 more
doaj +1 more source
Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder
Frontiers in Pharmacology, 2017 Guanosine (GUO) is a guanine-based purine nucleoside with important trophic functions and promising neuroprotective properties. Although the neuroprotective effects of GUO have been corroborated in cellular models of Parkinson’s disease (PD), its ...
Caio M. Massari +10 more
doaj +1 more source
Associations between purine metabolites and clinical symptoms in schizophrenia [PDF]
, 2012 Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology
Debra M. Montrose +9 more
core +3 more sources
Journal of Cell Biology, 2018 We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species.
J. McIntosh +8 more
semanticscholar +1 more source
Determination of total potentially available nucleosides in bovine milk [PDF]
, 2010 Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D. +2 more
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Guanosine Protects Neuronal PC12 Cells from Serum Deprivation-induced Cell Death
Pteridines, 2012 Survival of neurons is dependent on the presence of trophic and non-trophic factors. Previous findings showed that purine nucleosides have the potential to rescue cells from hypoxia-induced cell death. Here we demonstrate that purine nucleoside guanosine
Thauerer Bettina +5 more
doaj +1 more source