Results 21 to 30 of about 225,684 (400)

Electrocatalytic Oxidation of Guanine, Guanosine, and Guanosine Monophosphate [PDF]

Biophysical Journal, 2007
The electrochemical behavior of guanine, guanosine, and guanosine monophosphate (GMP) at redox polymer film modified indium tin oxide electrodes is examined by voltammetry and redox titration. Utilizing the redox polymer-coated electrodes as indicator electrodes, a new method for measuring the oxidation potentials, based on monitoring their catalytic ...
Xie, H., Yang, D., Heller, A., Gao, Z.
openaire   +3 more sources

Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model

Frontiers in Psychiatry, 2021
Major depressive disorder (MDD) leads to pervasive changes in the health of afflicted patients. Despite advances in the understanding of MDD and its treatment, profound innovation is needed to develop fast-onset antidepressants with higher effectiveness.
Roberto Farina Almeida, Yasmine Nonose, Marcelo Ganzella, Samanta Oliveira Loureiro, Andréia Rocha, Daniele Guilhermano Machado, Bruna Bellaver, Fernanda Urruth Fontella, Douglas T. Leffa, Letícia Ferreira Pettenuzzo, Gianina Teribele Venturin, Samuel Greggio, Jaderson Costa da Costa, Eduardo R. Zimmer, Eduardo R. Zimmer, Eduardo R. Zimmer, Elaine Elisabetsky, Diogo O. Souza   +17 more
doaj   +1 more source

GUANOSINE DIPHOSPHATE MANNOSE [PDF]

Journal of Biological Chemistry, 1954
Blanco y ...
Cabib, Enrico, Leloir, Luis Federico
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Guanosine Prevents Spatial Memory Impairment and Hippocampal Damage Following Amyloid-β_1–42 Administration in Mice

Metabolites, 2022
Alzheimer’s disease (AD) is a progressive neurodegenerative illness responsible for cognitive impairment and dementia. Accumulation of amyloid-beta (Aβ) peptides in neurons and synapses causes cell metabolism to unbalance, and the production of reactive ...
Victor Coelho, Luisa Bandeira Binder, Naiani Ferreira Marques, Leandra Celso Constantino, Gianni Mancini, Carla Inês Tasca   +5 more
doaj   +1 more source

Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets. [PDF]

Journal of Clinical Investigation, 1998
We isolated and identified nucleoside(5') oligophospho-(5') nucleosides containing adenosine and guanosine (ApnG; n = 3-6) as well as diguanosine polyphosphates (GpnG; n = 3-6) in human platelets. For identification, UV spectrometry, matrix-assisted laser desorption/ionization, postsource decay matrix-assisted laser desorption/ionization mass ...
Martin Tepel, Raimund Kaufmann, I Grobeta, Jerzy-Roch Nofer, Hartmut Schlüter, Joachim Jankowski, Walter Zidek, Jürgen Bachmann, Michael Karas, M. van der Giet, Gerd Assmann   +10 more
openaire   +3 more sources

Crystal structure of the nucleoside 2′-deoxyguanosine dimethyl sulfoxide disolvate

Acta Crystallographica Section E: Crystallographic Communications, 2023
The title compound, C10H13N5O4·2C2H6OS, which is of interest with respect to its biological activity, at 183 K has orthorhombic (P212121) crystal symmetry. The structure displays a network of intermolecular N—H...N, N—H...O and O—H...O hydrogen bonds. 2′-
Bernhard Spingler
doaj   +1 more source

Whole-genome analysis of Bacillus paranthracis YC06 isolated from healthy individual feces for biodegrading inosine and guanosine. [PDF]

BMC Microbiol
The overproduction of uric acid, driven by its key precursors (inosine and guanosine), leads to hyperuricemia, a metabolic disorder associated with severe complications such as gout and renal dysfunction.
Cao X, Zhang Y, Xu Q, Yan H.
europepmc   +2 more sources

Synthesis of microporous hydrogen-bonded supramolecular organic frameworks through guanosine self-assembly

Cell Reports Physical Science, 2021
Summary: Extending the structural hierarchy and complexity through small-molecular self-assembly is a powerful way to obtain large discrete, functional molecular architecture.
Ying He, Yanbin Zhang, Mengjia Liu, Kai Zhao, Chuan Shan, Lukasz Wojtas, Hao Guo, Aishun Ding, Xiaodong Shi   +8 more
doaj   +1 more source

Antibodies to guanosine [PDF]

FEBS Letters, 1984
Bovine serum albumin conjugates of guanosine prepared by the periodate method was used as immunogen to elicit guanosine antibodies in rabbits. The specificities of the antibodies were studied by the inhibition of their binding to [3H]Gox‐red, [32P]DNA and [3H]RNA by related non‐radioactive compounds.
Iswari, S, Jacob, TM
openaire   +3 more sources

Purine metabolism rewiring improves glioblastoma susceptibility to temozolomide treatment. [PDF]

Cell Death Dis
Glioblastoma (GBM) is among the deadliest cancers, characterized by poor prognosis and median survival of 12–15 months post-diagnosis. Despite aggressive therapeutic regimens, GBM treatment is still an unmet clinical need due to heterogeneity ...
D'Aprile S, Denaro S, Torrisi F, Longhitano L, Giallongo S, Giallongo C, Bontempi V, Bucolo C, Drago F, Mione MC, Li Volti G, Potokar M, Jorgačevski J, Zorec R, Tibullo D, Amorini AM, Vicario N, Parenti R.   +17 more
europepmc   +2 more sources