Results 71 to 80 of about 194,604 (252)

Salmonella Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress

mBio, 2018
The adaptations that protect pathogenic microorganisms against the cytotoxicity of nitric oxide (NO) engendered in the immune response are incompletely understood.
Liam F. Fitzsimmons, Lin Liu, Ju-Sim Kim, Jessica Jones-Carson, Andrés Vázquez-Torres   +4 more
doaj   +1 more source

MPP+-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine [PDF]

, 2007
Guanosine exerts neuroprotective effects in the central nervous system. Apoptosis, a morphological form of programmed cell death, is implicated in the pathophysiology of Parkinson’s disease (PD).
A Bonni, A Brunet, A Hartmann, A Hartmann, A Nicotra, C Bernstein, C Gómez, C Gómez-Santos, Christian Bau, CP Fall, CS Lee, CW Olanow, DE Bredesen, DP Brazil, E Maries, EN Shiozaki, Eva S. Werstiuk, F Fornai, G Kroemer, G Kroemer, G Milligan, H Dudek, H Wang, H Zhou, HR Kaslow, Iolanda D’Alimonte, J Kakimura, J Xu, JE Chipuk, Kathleen M. Pettifer, KM Boatright, KM Pettifer, LA Allan, M Hetman, M Lopez-Ilasaca, M Lopez-Ilasaca, M Vila, M Vila, M Vila, MC Abraham, MG Spillantini, MH Polymeropoulos, Michel P. Rathbone, MJ Marinissen, MP Rathbone, MP Wymann, MT Lin, NA Tatton, NA Tatton, P Iorio Di, P Iorio Di, Patrizia Ballerini, PC Waldmeier, R Yao, RJ Smeyne, RK Sunahara, S Krantic, S Kumar, S Nagata, S Nagata, S Przedborski, S Sato, S Subba Rao, SA Baldwin, SC Benn, SG Kennedy, Shucui Jiang, SK Sharma, SR Datta, SV Kalivendi, T Katada, T Wada, TD King, TF Franke, U Traversa, U Traversa, V Viswanath, W Dauer, W Maruyama, W Meissner, X-J Wang, Y Gavrieli, Y Itano, Y Kitamura, Z Xia   +84 more
core   +2 more sources

Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.

Endocrine reviews, 2006
Natriuretic peptides are a family of structurally related but genetically distinct hormones/paracrine factors that regulate blood volume, blood pressure, ventricular hypertrophy, pulmonary hypertension, fat metabolism, and long bone growth. The mammalian
L. Potter, Sarah E. Abbey-Hosch, D. Dickey   +2 more
semanticscholar   +1 more source

Observation of a Change in Bend of an RNA Kissing Complex Using the Angular Dependence of Fluorescence Resonance Energy Transfer [PDF]

, 2014
We report on the observation of a change in the bend angle of an RNA kissing complex upon Rop binding using single-molecular-pair FRET. The angular relationship between the dyes, rather than the distance between them, is shown to be responsible for the observed change in energy transfer. It has long been thought that Rop increases the bend angle of the
arxiv   +1 more source

Increased production of inosine and guanosine by means of metabolic engineering of the purine pathway in Ashbya gossypii

Microbial Cell Factories, 2015
BackgroundInosine and guanosine monophosphate nucleotides are convenient sources of the umami flavor, with attributed beneficial health effects that have renewed commercial interest in nucleotide fermentations ...
Rodrigo Ledesma‐Amaro, R. Buey, J. Revuelta   +2 more
semanticscholar   +1 more source

Construction of Supramolecular Organogel with Circularly Polarized Luminescence by Self-Assembled Guanosine Octamer

Cell Reports Physical Science, 2020
Summary: Gel formation using guanosine self-assembly is an important process in supramolecular chemistry. Here, we report the stepwise construction of circularly polarized luminescent supramolecular organogels from self-assembled guanosine quadruplexes ...
Yanbin Zhang, Ying He, Lukasz Wojtas, Xiaodong Shi, Hao Guo   +4 more
doaj  

Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA.

Journal of the American Chemical Society, 2015
The archetypical fluorescent nucleoside analog, 2-aminopurine (2Ap), has been used in countless assays, though it suffers from very low quantum yield, especially when included in double strands, and from the fact that its residual emission frequently ...
M. Sholokh, Rajhans Sharma, Dongwon Shin, R. Das, O. Zaporozhets, Y. Tor, Y. Mély   +6 more
semanticscholar   +1 more source

Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]

, 1992
1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G., Gratzl, Manfred, Rosenthal, W., Spicher, K., Stecher, B., Wegenhorst, U.   +5 more
core  

Effect of GTP and Ca2+ on inositol 1,4,5-trisphosphate induced Ca2+ release from permeabilized rat exocrine pancreatic acinar cells [PDF]

, 1991
The effects of Ca2+ and GTP on the release of Ca2+ from the inositol 1,4,5-trisphosphate (IP3) sensitive Ca2+ compartment were investigated with digitonin permeabilized rat pancreatic acinar cells.
Ammann, Amsterdam, Bayerdörffer, Berridge, Brass, Chueh, Comerford, Danoff, Dawson, Dawson, Föhr, Ghosh, Gill, Henne, Hurley, Imamura, Joseph, Kemmer, Kimura, Kleinecke, Prentki, Rossier, Simon, Stoehr, Streb, Streb, Suppattapone, Thomas, Ueda, Willems, Worley   +30 more
core   +1 more source

Hierarchical Formation of Fibrillar and Lamellar Self-Assemblies from Guanosine-Based Motifs

Journal of Nucleic Acids, 2010
Here we investigate the supramolecular polymerizations of two lipophilic guanosine derivatives in chloroform by light scattering technique and TEM experiments.
Paolo Neviani, Dominique Sarazin, Marc Schmutz, Christian Blanck, Nicolas Giuseppone, Gian Piero Spada   +5 more
doaj   +1 more source