Results 81 to 90 of about 197,885 (298)

Liberators of NO exert a dual effect on renin secretion from isolated mouse renal juxtaglomerular cells [PDF]

open access: yes, 1993
This study aimed to examine the role of nitric oxide (NO) in the regulation of renin secretion from renal juxtaglomerular (JG) cells. Using primary cultures of mouse renal JG cells, we found that sodium nitroprusside (SNP) and 3-morpholino-sydnonimin ...
Kurtz, Armin, Schricker, K.
core   +1 more source

Stability analysis of a signaling circuit with dual species of GTPase switches [PDF]

open access: yesarXiv, 2020
GTPases are molecular switches that regulate a wide range of cellular processes, such as organelle biogenesis, position, shape, and signal transduction. These enzymes operate by toggling between an active ("ON") guanosine triphosphate (GTP)-bound state and an inactive ("OFF") guanosine diphosphate (GDP)-bound state; such a toggle is regulated by GEFs ...
arxiv  

Shear-Induced Nitric Oxide Production by Endothelial Cells [PDF]

open access: yes, 2016
We present a biochemical model of the wall shear stress (WSS)-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell (EC). The model includes three key mechanotransducers: mechanosensing ion channels, integrins and G-protein-coupled receptors. The reaction cascade consists of two interconnected parts.
arxiv   +1 more source

Salmonella Reprograms Nucleotide Metabolism in Its Adaptation to Nitrosative Stress

open access: yesmBio, 2018
The adaptations that protect pathogenic microorganisms against the cytotoxicity of nitric oxide (NO) engendered in the immune response are incompletely understood.
Liam F. Fitzsimmons   +4 more
doaj   +1 more source

Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]

open access: yes, 1986
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.   +5 more
core   +1 more source

Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.

open access: yesEndocrine reviews, 2006
Natriuretic peptides are a family of structurally related but genetically distinct hormones/paracrine factors that regulate blood volume, blood pressure, ventricular hypertrophy, pulmonary hypertension, fat metabolism, and long bone growth. The mammalian
L. Potter   +2 more
semanticscholar   +1 more source

15N NMR study of a mixture of uniformly labeled tRNAs [PDF]

open access: yes, 1982
15N NMR spectra were taken of 15N-enriched tRNA extracted from bakers yeast; ammonium sulfate was used as a nitrogen source. The increase in the degree of denaturation of tRNA, which occurs with increase in temperature from 30 degrees C to 70 degrees C ...
Birdseye, Theresa R.   +3 more
core   +1 more source

Effects of Guanosine Tetraphosphate, Guanosine Pentaphosphate, and β-γ Methylenyl-Guanosine Pentaphosphate on Gene Expression of Escherichia coli In Vitro [PDF]

open access: yesProceedings of the National Academy of Sciences, 1974
The effects of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), both produced by E. coli , were measured on the activities of several genes in a cell-free system. Gene activity is measured as gene-directed synthesis of biochemically competent protein or transfer RNA.
Geoffrey Zubay   +4 more
openaire   +2 more sources

Increased production of inosine and guanosine by means of metabolic engineering of the purine pathway in Ashbya gossypii

open access: yesMicrobial Cell Factories, 2015
BackgroundInosine and guanosine monophosphate nucleotides are convenient sources of the umami flavor, with attributed beneficial health effects that have renewed commercial interest in nucleotide fermentations ...
Rodrigo Ledesma‐Amaro   +2 more
semanticscholar   +1 more source

Construction of Supramolecular Organogel with Circularly Polarized Luminescence by Self-Assembled Guanosine Octamer

open access: yesCell Reports Physical Science, 2020
Summary: Gel formation using guanosine self-assembly is an important process in supramolecular chemistry. Here, we report the stepwise construction of circularly polarized luminescent supramolecular organogels from self-assembled guanosine quadruplexes ...
Yanbin Zhang   +4 more
doaj  

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