Results 81 to 90 of about 225,684 (400)
The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]
, 2018 Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca +5 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]
, 1992 1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G. +5 more
core
Microbial Cell Factories, 2015 BackgroundInosine and guanosine monophosphate nucleotides are convenient sources of the umami flavor, with attributed beneficial health effects that have renewed commercial interest in nucleotide fermentations ...
Rodrigo Ledesma‐Amaro +2 more
semanticscholar +1 more source
Effects of Guanosine Tetraphosphate, Guanosine Pentaphosphate, and β-γ Methylenyl-Guanosine Pentaphosphate on Gene Expression of Escherichia coli In Vitro [PDF]
Proceedings of the National Academy of Sciences, 1974 The effects of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), both produced by E. coli , were measured on the activities of several genes in a cell-free system. Gene activity is measured as gene-directed synthesis of biochemically competent protein or transfer RNA.
Geoffrey Zubay +4 more
openaire +2 more sources
Bioactive Materials, 2022 Bacterial keratitis is the most common corneal infection which may lead to blindness, and seriously threatened the human visual health worldwide. Clinical treatment with antibiotic eye drops formulation usually falls in low bioavailability and poor ...
Xuejing Cheng +5 more
doaj +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. [PDF]
, 2017 A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization.
Fin, Andrea +2 more
core +1 more source
Conformation, hydrogen bonding and aggregate formation of guanosine 5′-monophosphate and guanosine in dimethylsulfoxide [PDF]
Nucleic Acids Research, 1994 The tetrabutylammonium salt of guanosine 5'-monophosphate (5'-GMP) dissolves in DMSO-d6 forming aggregated species which exhibit some properties of reverse micelles. 1H NOESY experiments show that the 5'-GMP adopts the syn conformation about the glycosidic bond.
Judith A. Walmsely +3 more
openaire +2 more sources
Advanced Materials Technologies, EarlyView.This review highlights advances in printing with nano‐ and microparticulate diamond for applications such as sensors, thermal management, machining tools, and biointerfaces. By covering screen, inkjet, microcontact, and 3D printing techniques, it outlines how diamond particles can be integrated into composite materials and functional devices, while ...
Simona Baluchová +1 more
wiley +1 more source