Results 101 to 110 of about 163,448 (315)

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source

Effects of insulin and guanosine 5′-[γ-thio]triphosphate on fatty acid synthesis and lipolysis within electropermeabilized fat-cells [PDF]

, 1992
Guy A. Rutter, Richard M. Denton
openalex   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Supplementary Figure 2C from Exon Array Analyses across the NCI-60 Reveal Potential Regulation of TOP1 by Transcription Pausing at Guanosine Quartets in the First Intron

, 2023
William C. Reinhold, Jean‐Louis Mergny, Hongfang Liu, Michael T. Ryan, Thomas D. Pfister, Robert J. Kinders, Ralph E. Parchment, James H. Doroshow, John N. Weinstein, Yves Pommier   +9 more
openalex   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

Guanine-Based Purines as an Innovative Target to Treat Major Depressive Disorder

Frontiers in Pharmacology, 2021
Roberto F. Almeida, Roberto F. Almeida, Tiago P. Ferreira, Camila V. C. David, Paulo C. Abreu e Silva, Sulamita A. dos Santos, Ana L. S. Rodrigues, Elaine Elisabetsky   +7 more
doaj   +1 more source

Molybdenum–Gold Nanoclusters Using 2-Mercapto-5-nitrobenzimidazole as Ligand for Sensing Guanosine and Mg Ions Through a Fluorescence Turn Off–On Mechanism

Applied Spectroscopy Practica
In this study, a new sensor for the fluorescence detection of guanosine and Mg 2+ ions using a “turn-off–on” mechanism was successfully constructed using 2-mercapto-5-nitrobenzimidazole (MNB) modified bimetallic molybdenum–gold nanoclusters (Mo-AuNCs ...
Harshita, Hirakendu Basu, Tae Jung Park, Suresh Kumar Kailasa   +3 more
doaj   +1 more source

Synthesis, characterization, and biological activities of new conjugates of Guanosine grafted on polyvinyl alcohol, carbohydrate chitosan, and cellulose [PDF]

, 2022
Sabry El-Naggar, A. A. EL‐BARBARY, Yehia A. Hafez, Wesam M. Salama, Hazem M. Elkholy, Mohamed Mounir Shaker   +5 more
openalex   +1 more source

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, EarlyView.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source

Simple Guanosine—Amino Acid Hybrids as Low Molecular Weight Hydrogelators

Chemistry – A European Journal, EarlyView.
Unexplored guanosine‐amino acid derivatives act as low molecular weight hydrogelators. Gelation is triggered by K+ ions and pH changes and relies on G‐quadruplex formation. Small changes in the amino acid structure have a strong impact on the mechanical properties of the gels.
Silvia Pieraccini, Samuele Ruffoli, Martina Occhi, Demetra Giuri, Devis Montroni, Claudia Tomasini, Stefano Masiero   +6 more
wiley   +1 more source