Results 121 to 130 of about 118,645 (287)

Exome sequencing identifies a novel mutation of the GDI1 gene in a Chinese non-syndromic X-linked intellectual disability family

Genetics and Molecular Biology, 2017
X-linked intellectual disability (XLID) has been associated with various genes. Diagnosis of XLID, especially for non-syndromic ones (NS-XLID), is often hampered by the heterogeneity of this disease.
Yongheng Duan, Sheng Lin, Lichun Xie, Kaifeng Zheng, Shiguo Chen, Hui Song, Xuchun Zeng, Xueying Gu, Heyun Wang, Linghua Zhang, Hao Shao, Wenxu Hong, Lijie Zhang, Shan Duan   +13 more
doaj   +1 more source

Targeted LC-MS profiling reveals dysregulated glycolytic flux and TCA cycle stalling in POAG plasma

Scientific Reports
Glaucoma is the leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is the most common form globally and has been linked to mitochondrial dysfunction and energy deficiency.
Yizhen Tang, Xuanqi Zhang, Xiaoxiao Chen, Jiayong Li, Minyue Xie, Qianru Wu, Yinghan Zhang, Chi-wai Do, Xinghuai Sun   +8 more
doaj   +1 more source

Guanosine diphosphate glucose and guanosine diphosphate fructose from Eremothecium ashbyii [PDF]

Biochemical Journal, 1959
H G, PONTIS, A L, JAMES, J, BADDILEY
openaire   +3 more sources

Chemical Synthesis of Guanosine Diphosphate Mannose (GDPM)

Chemical and Pharmaceutical Bulletin, 1959
Guanosine diphosphate mannose (GDPM), coenzyme of mannose polymerization, was chemically synthesized. GMP and cyclohexylamine were condensed to form N-cyclohexylphosphoramidate in the presence of DCC. The amidate (III) was reacted with benzyl hydrogen phosphate and after hydrogenation led to GDP (V).
Tohru Ueda, Eiko Ohtsuka
openaire   +2 more sources

Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

European Journal of Histochemistry, 2012
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production.
A. Amaroli, M.G. Chessa
doaj   +1 more source

Versatile enzymatic system for the production of guanosine polyphosphates [PDF]

, 2010
Posters - ED02 Signalling and systems biology: abstract no. ED02/20During periods of environmental stress, bacteria synthesize guanosine tetraphosphate (ppGpp, magic spot I) and guanosine pentaphosphate (pppGpp, magic spot II) in a process known as the ...
Choi, MMY, Wang, Y, Watt, RM
core  

Hydrogen bonding, spectroscopic (FT-IR and FT-Raman), UV−Vis, and Mulliken charge analysis of Guanosine-5′ -Diphosphate: insight from DFT and molecular docking

Bibechana
Hybrid functional B3LYP has been used for quantum chemical calculation of Guanosine-5′ -Diphosphate (GDP) from DFT approach. The intra-molecular hydrogen bonding in the title molecule was rendered from Quantum theory of atoms in molecule (QTAIM).
Manoj Kumar Chaudhary, Tarun Chaudhary, Bhawani Datt Joshi, Gulab Singh Verma, Rajesh Kumar Shukla, Tirth Raj Paneru   +5 more
doaj   +1 more source

Inhibition of agonist-induced platelet aggregation, Ca2+ mobilization and granule secretion by guanosine 5′-[β-thio]diphosphate and GDP in intact platelets. Evidence for an inhibitory mechanism unrelated to the inhibition of G-protein-GTP interaction [PDF]

, 1988
S Krishnamurthi, Y Patel, V V Kakkar
openalex   +1 more source

5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]

, 2013
Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád, Juhász, Gábor, Kovács, Zsolt, Kékesi, Katalin A.   +3 more
core  

Template-directed biopolymerization: tape-copying Turing machines

, 2012
DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using another linear ...
Chowdhury, Debashish, Sharma, Ajeet K.
core   +1 more source