Results 101 to 110 of about 66,472 (220)

Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi   +9 more
wiley   +1 more source

Targeted LC-MS profiling reveals dysregulated glycolytic flux and TCA cycle stalling in POAG plasma

open access: yesScientific Reports
Glaucoma is the leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is the most common form globally and has been linked to mitochondrial dysfunction and energy deficiency.
Yizhen Tang   +8 more
doaj   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao   +4 more
wiley   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao   +8 more
wiley   +1 more source

5'-diphosphate-guanosine-3'-diphosphate (ppGpp) stimulates the degradation of certain proteins by ATP-dependent protease La from Escherichia coli

open access: yes, 1992
During starvation, Escherichia coli increase their rate of breakdown of pre-existing cell proteins from 2- to 4-fold. This response requires ATP and an accumulation of 5'-diplios-phate-guanosine-3'-diphosphate (ppGpp).
Sang Ki Park   +5 more
core  

Advanced Binary Guanosine and Guanosine 5'‑Monophosphate Cell-Laden Hydrogels for Soft Tissue Reconstruction by 3D Bioprinting

open access: yes, 2023
Soft tissue defects or pathologies frequently necessitate the use of biomaterials that provide the volume required for subsequent vascularization and tissue formation as autrografts are not always a feasible alternative.
Maria Merino-Gómez   +17 more
core   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

Mtb Pck Amino acid (AA) residues forming hydrogen bonds and close contacts (˂ 3.7Å) with guanosine-5'-diphosphate (GDP) in Mtb Pck-GDP-Mn2+ complex.

open access: yes, 2015
Mtb Pck Amino acid (AA) residues forming hydrogen bonds and close contacts (˂ 3.7Å) with guanosine-5'-diphosphate (GDP) in Mtb Pck-GDP-Mn2+ complex.
Iva Machová (709377)   +9 more
core   +1 more source

Comparison of the stabilities and solution structures of metal ion complexes formed with 5'-di- and 5'-triphosphates of purine nucleosides [PDF]

open access: yes, 2003
Nucleotides and metal ions are involved in the basic metabolic processes of life, participating as substrates in enzymatic reactions in the form of metal ion complexes.
Minari Bianchi, Emanuela
core   +1 more source

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