Results 91 to 100 of about 30,288 (231)

Ribozyme für die RNA‐katalysierte Methylierung und Markierung von RNA

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
Ribozyme sind vielseitige Werkzeuge für die präzise Modifikation von RNA. Das Reaktionsspektrum in‐vitro‐selektierter Ribozyme reicht vom Einbau funktioneller Gruppen und Fluorophoren bis zu natürlichen RNA‐Methylierungen. Dieser Übersichtsartikel präsentiert Cofaktor‐abhängige Ribozyme für die positionsgenaue Markierung und Modifikation von RNA ...
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Schematic representation of the ITPA involvement in 6-MP metabolism and endogenous purine metabolism.

, 2014
6-MP, 6-mercaptopurine; 6-MMP, 6-methylmercaptopurine; TIMP, thioinosine monophosphate; TIDP, thioinosine diphosphate; TITP, thioinosine triphosphate; MeTITP, methylthioinosine triphosphate; TGMP, thioguanosine monophosphate; TGDP, thioguanosine ...
Miha Milek (642550), Irena Mlinaric-Rascan (313386), Alenka Smid (642548), Natasa Karas-Kuzelicki (642549), Janez Jazbec (50070)   +4 more
core   +1 more source

Ginsenoside Re inhibits pacemaker potentials via adenosine triphosphate-sensitive potassium channels and the cyclic guanosine monophosphate/nitric oxide-dependent pathway in cultured interstitial cells of Cajal from mouse small intestine

Journal of Ginseng Research, 2015
Background: Ginseng belongs to the genus Panax. Its main active ingredients are the ginsenosides. Interstitial cells of Cajal (ICCs) are the pacemaker cells of the gastrointestinal (GI) tract.
Noo Ri Hong, Hyun Soo Park, Tae Seok Ahn, Hyun Jung Kim, Ki-Tae Ha, Byung Joo Kim   +5 more
doaj   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, Volume 65, Issue 23, 1 June 2026.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

Guanosine diphosphate binding to brown adipose tissue mitochondria is increased after single meal

, 1985
A single meal results in an increased thermic activity of brown adipose tissue (BAT). The purpose of the present studies was threefold: 1) to identify major metabolic origins involved in this thermic response, 2) to determine the effect of meal ...
M. Saito, G. A. Bray, J. R. Lupien, Z. Glick   +3 more
core   +1 more source

Discovering and Targeting Dynamic Drugging Pockets of Oncogenic Proteins: The Role of Magnesium in Conformational Changes of the G12D Mutated Kirsten Rat Sarcoma-Guanosine Diphosphate Complex. [PDF]

Int J Mol Sci, 2022
Hu Z, Marti J.
europepmc   +1 more source

Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin, Anuradha U. K. H. Bambarandhage, Michelle Moreno Escalona, Dimitra Ivanova, Tim Gate, Helen Tench, Manfred Beckman, Helen Phillips, Mandana Pennick, Luis A. J. Mur   +9 more
wiley   +1 more source

Versatile enzymatic system for the production of guanosine polyphosphates [PDF]

, 2010
During periods of environmental stress, bacteria synthesize guanosine tetraphosphate (ppGpp, magic spot I) and guanosine pentaphosphate (pppGpp, magic spot II) in a process known as the stringent response.
Wang, Y, Watt, RM, Choi, MMY
core  

Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: New evidence for a putative novel function of uncoupling proteins as superoxide anion transporters

, 2012
In this report, we show new experimental evidence that, in mouse brain mitochondria, uncoupling protein-2 (UCP2) can be involved in superoxide (O2-) removal from the mitochondrial matrix.
PINTON, Paolo, Shabalina I, BONORA, Massimo, Więckowski MR, Schönfeld P, Suski JM   +5 more
core   +2 more sources

Targeted LC-MS profiling reveals dysregulated glycolytic flux and TCA cycle stalling in POAG plasma

Scientific Reports
Glaucoma is the leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is the most common form globally and has been linked to mitochondrial dysfunction and energy deficiency.
Yizhen Tang, Xuanqi Zhang, Xiaoxiao Chen, Jiayong Li, Minyue Xie, Qianru Wu, Yinghan Zhang, Chi-wai Do, Xinghuai Sun   +8 more
doaj   +1 more source