Results 121 to 130 of about 1,634 (145)

The Effect of Guanosine Tetraphosphate (ppGpp), and P-Y-Methylene Guanosine Pentaphosphate (ppGppp) on E. coli Gene Expression

open access: yes, 2009
楊惠郎;Zubay, G.;Urm, E.;Reiness, G.;Cashel, M.   +1 more
core  

Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity. [PDF]

open access: yesmBio
She F   +9 more
europepmc   +1 more source

The impact of bacterial purine metabolism on antibiotic efficacy. [PDF]

open access: yesNPJ Antimicrob Resist
Stevens CE, Deventer AT, Hobbs JK.
europepmc   +1 more source

Pathogenicity and virulence of <i>Erwinia amylovora</i>. [PDF]

open access: yesVirulence
Sundin GW, Castiblanco LF, Zeng Q.
europepmc   +1 more source

Live‐Cell Imaging of Guanosine Tetra‐ and Pentaphosphate (p)ppGpp with RNA‐based Fluorescent Sensors**

Angewandte Chemie - International Edition, 2021
AbstractGuanosine tetra‐ and pentaphosphate, (p)ppGpp, are important alarmone nucleotides that regulate bacterial survival in stressful environment. A direct detection of (p)ppGpp in living cells is critical for our understanding of the mechanism of bacterial stringent response. However, it is still challenging to image cellular (p)ppGpp.
Zhining Sun, Rigumula Wu, Bin Zhao
exaly   +3 more sources

Structural Characterization of the Stringent Response Related Exopolyphosphatase/Guanosine Pentaphosphate Phosphohydrolase Protein Family,

open access: yesBiochemistry, 2004
Exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) enzymes play central roles in the bacterial stringent response induced by starvation. The high-resolution crystal structure of the putative Aquifex aeolicus PPX/GPPA phosphatase from the actin-like ATPase domain superfamily has been determined, providing the first insights to ...
Kristensen, Ole   +4 more
openaire   +4 more sources

Preparation of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) from Escherichia coli ribosomes

Analytical Biochemistry, 1974
Abstract A means of preparative enzymatic synthesis of guanosine tetraphosphate (ppGpp), guanosine pentaphosphate (pppGpp), and related derivatives is deseribed. The Escherichia coli ribosomes can be recovered, stored, and used repeatedly as a source of synthetic activity.
Michael Cashel
exaly   +3 more sources

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