Results 111 to 120 of about 46,501 (205)

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host

open access: yesmBio, 2017
Serious bacterial infections in immunocompromised patients require highly effective antibacterial therapy for cure, and thus, this setting may reveal novel mechanisms by which bacteria circumvent antibiotics in the absence of immune pressure.
Erin S. Honsa   +12 more
doaj   +1 more source

Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p) ppGpp synthase

open access: yes, 2006
Brockmann-Gretza O, Kalinowski J. Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p) ppGpp synthase. BMC Genomics.
Brockmann-Gretza Olaf   +5 more
core   +1 more source

A Dopamine-Responsive Signal Transduction Controls Transcription of Salmonella enterica Serovar Typhimurium Virulence Genes

open access: yesmBio, 2019
We have shown that the ligand-responsive MarR family member SlyA plays an important role in transcription activation of multiple virulence genes in Salmonella enterica serovar Typhimurium by responding to guanosine tetraphosphate (ppGpp).
Dezhi Yang   +4 more
doaj   +1 more source

The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC

open access: yesmBio, 2019
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which ...
James A. Kraemer   +2 more
doaj   +1 more source

High Intracellular Level of Guanosine Tetraphosphate in Mycobacterium smegmatis Changes the Morphology of the Bacterium

open access: yes, 2000
Almost one-third of the world population today harbors the tubercle bacillus asymptomatically. It is postulated that the morphology and staining pattern of the long-term persistors are different from those of actively growing culture.
Mukherjee, Tapan K   +2 more
core  

The differential effects of guanosine tetraphosphate on open complex formation at the Escherichia coli ribosomal protein promoters rplJ and rpsA P1

open access: yes, 1998
The effects of guanosine tetraphosphate (ppGpp) on inhibition of single-round in vitro transcription and on the kinetics of open complex formation were investigated at the Escherichia coli ribosomal protein promoters rplJ and rpsA P1.
Chatterji, Dipankar   +2 more
core   +1 more source

A study of bacterial response to polypeptide antibiotics.

open access: yes, 1983
International audienceWhen Escherichia coli cells are treated with either polymixin or gramicidin at concentrations that block protein and RNA synthesis, they accumulate a significant amount of guanosine tetraphosphate ppGpp.
Cortay, Jc, Cozzone, Aj
core   +2 more sources

Occurrence of millimolar concentrations of guanosine (5′)tetraphospho(5′)guanosine (Gp4G) in encysted embryos of Thamnocephalus platyurus

open access: yes, 2013
One gram of encysted embryo of Thamnocephalus platyurus (an anostracan crustacea) contains around 17 μmoles of diguanosine tetraphosphate (Gp4G) and 390 mg of protein, and traces of diguanosine triphosphate (Gp3G). The identity of Gp4G was established by
Günther Sillero, María A.   +4 more
core   +1 more source

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