Results 91 to 100 of about 4,703 (162)

The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression

BMC Genomics, 2012
Background Invasion of intestinal epithelial cells by Salmonella enterica serovar Typhimurium (S. Typhimurium) requires expression of the extracellular virulence gene expression programme (STEX), activation of which is dependent on the signalling ...
Ramachandran Vinoy K, Shearer Neil, Jacob Jobin J, Sharma Cynthia M, Thompson Arthur   +4 more
doaj   +1 more source

Physiology and Transcriptional Analysis of (p)ppGpp-Related Regulatory Effects in Corynebacterium glutamicum

Frontiers in Microbiology, 2019
The alarmone species ppGpp and pppGpp are elementary components of bacterial physiology as they both coordinate the bacterial stress response and serve as fine-tuners of general metabolism during conditions of balanced growth.
Matthias Ruwe, Marcus Persicke, Tobias Busche, Benjamin Müller, Jörn Kalinowski   +4 more
doaj   +1 more source

Guanosine tetraphosphate (ppGpp) is a new player in Brassica napus L. seed development

Food Chemistry
Rapeseed oil, constituting 12% of global vegetable oil production, is susceptible to quality degradation due to stress-induced incomplete seed degreening, fatty acid oxidation, or poor nutrient accumulation. We hypothesise that the hyperphosphorylated nucleotide alarmone ppGpp (guanosine tetraphosphate), acts as a pivotal regulator of these processes ...
Turkan, Sena, Kulasek, Milena, Zienkiewicz, Agnieszka, Mierek-Adamska, Agnieszka, Skrzypek, Edyta, Warchoł, Marzena, Szydłowska-Czerniak, Aleksandra, Bartoli, Julia, Field, Ben, Dąbrowska, Grażyna   +9 more
openaire   +2 more sources

From Dormancy to Eradication: Strategies for Controlling Bacterial Persisters in Food Settings

Foods
Bacterial persistence, a dormant state that enables microorganisms to survive harsh conditions, is a significant concern in food-industry settings, where traditional antimicrobial treatments often fail to eliminate these resilient cells.
Susana Serrano, Mirjana Ž. Grujović, Katarina G. Marković, Maria Teresa Barreto-Crespo, Teresa Semedo-Lemsaddek   +4 more
doaj   +1 more source

Cell-length heterogeneity: a population-level solution to growth/virulence trade-offs in the plant pathogen Dickeya dadantii.

PLoS Pathogens, 2019
Necrotrophic plant pathogens acquire nutrients from dead plant cells, which requires the disintegration of the plant cell wall and tissue structures by the pathogen.
Zhouqi Cui, Ching-Hong Yang, Roshni R Kharadi, Xiaochen Yuan, George W Sundin, Lindsay R Triplett, Jie Wang, Quan Zeng   +7 more
doaj   +1 more source

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host

mBio, 2017
Serious bacterial infections in immunocompromised patients require highly effective antibacterial therapy for cure, and thus, this setting may reveal novel mechanisms by which bacteria circumvent antibiotics in the absence of immune pressure.
Erin S. Honsa, Vaughn S. Cooper, Mohammed N. Mhaissen, Matthew Frank, Jessica Shaker, Amy Iverson, Jeffrey Rubnitz, Randall T. Hayden, Richard E. Lee, Charles O. Rock, Elaine I. Tuomanen, Joshua Wolf, Jason W. Rosch   +12 more
doaj   +1 more source

The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC

mBio, 2019
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which ...
James A. Kraemer, Allen G. Sanderlin, Michael T. Laub   +2 more
doaj   +1 more source

The Isolation of Guanosine Tetraphosphate from Commercially Available Preparations of Guanosine Triphosphate

Journal of Biological Chemistry, 1965
J A, GARDNER, M B, HOAGLAND
openaire   +2 more sources

Phenotypic fate differentiation and its mechanism in Cronobacter sakazakii under different chlorine concentrations

Journal of Dairy Science
: Cronobacter sakazakii is a significant foodborne pathogen commonly found in dairy processing environments. Under chlorine stress, C. sakazakii may survive by adopting stress-resistant phenotypes such as biofilm and viable but nonculturable (VBNC) state.
Jingfeng Zhang, Yunshao Mo, Ying Sun, Haoqing Zhao, Lei Shi, Lichao Zhao   +5 more
doaj   +1 more source

Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. [PDF]

Sci Rep, 2018
Tapscott T, Kim JS, Crawford MA, Fitzsimmons L, Liu L, Jones-Carson J, Vázquez-Torres A.   +6 more
europepmc   +1 more source