Results 81 to 90 of about 46,501 (205)

Effect of guanosine tetraphosphate on growth rate and stable RNA synthesis in \u3ci\u3eEscherichia coli\u3c/i\u3e [PDF]

, 2002
Guanosine tetraphosphate (ppGpp) is a good candidate for a stable RNA synthesis regulator at different growth rates because: high ppGpp levels present during the stringent response are known to inhibit stable RNA synthesis, and there is an inverse ...
Quintanilla, Heather Anne
core  

Synthesis and turnover of basal level guanosine tetraphosphate in Escherichia coli.

Journal of Biological Chemistry, 1975
Cultures of escherichia coli growing exponentially in Trisacetate medium were subjected to nutritional shift-up and the pool size of guanosine 5'-3'-diphosphate-3'diphosphate (ppGpp) as well as the rates of protein synthesis and net RNA synthesis were determined.
J D, Friesen, N P, Fiil, K, von Meyenburg   +2 more
openaire   +2 more sources

ppGpp Controlled by the Gac/Rsm Regulatory Pathway Sustains Biocontrol Activity in Pseudomonas fluorescens CHA0

Molecular Plant-Microbe Interactions, 2012
In Pseudomonas fluorescens CHA0 and other fluorescent pseudomonads, the Gac/Rsm signal transduction pathway is instrumental for secondary metabolism and biocontrol of root pathogens via the expression of regulatory small RNAs (sRNAs).
Kasumi Takeuchi, Kosumi Yamada, Dieter Haas   +2 more
doaj   +1 more source

The stringent response regulator (p) ppGpp mediates virulence gene expression and survival in Erwinia amylovora

BMC Genomics, 2020
Background The nucleotide second messengers, i.e., guanosine tetraphosphate and pentaphosphate [collectively referred to as (p) ppGpp], trigger the stringent response under nutrient starvation conditions and play an essential role in virulence in the ...
Ho-wen Yang, Menghao Yu, Jae Hoon Lee, Tiyakhon Chatnaparat, Youfu Zhao   +4 more
doaj   +1 more source

The elongation factor Tu from Escherichia coli, aminoacyl-tRNA, and guanosine tetraphosphate form a ternary complex which is bound by programmed ribosomes.

Journal of Biological Chemistry, 1983
The interaction of the Escherichia coli elongation factor Tu guanosine tetraphosphate complex (EF-Tu ppGpp) with aminoacyl-tRNAs(aa-tRNA) was reinvestigated by gel filtration and hydrolysis protection experiments.
A. Pingoud, F. Gast, W. Block, F. Peters
semanticscholar   +1 more source

Clavibacter michiganensis Reframed: The Story of How the Genomics Era Made a New Face for an Old Enemy

Molecular Plant Pathology, Volume 26, Issue 5, May 2025.
We provide a historical perspective and an updated overview on the aetiology, epidemiology and management strategies of tomato bacterial canker caused by Clavibacter michiganensis. ABSTRACT Objective Bacterial wilt and canker of tomato caused by the gram‐positive corynebacterial species Clavibacter michiganensis is an economically important disease ...
Ebrahim Osdaghi, Hamid Abachi, Marie‐Agnes Jacques   +2 more
wiley   +1 more source

Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis

, 2022
Diadenosine tetraphosphate (Ap4A) is a putative second messenger molecule that is conserved from bacteria to humans. Nevertheless, its physiological role and the underlying molecular mechanisms are poorly characterized.
Anja Paulus, Yang, J., Bange, G., Wang, J., Gert Bange, Young, M.K.M., Mais, C., Georg Hochberg, Wieland Steinchen, Megan K. M. Young, Jin Yang, Amador-Noguez, D., Hochberg, G., Giammarinaro, P.I., Wang, J.D., Pietro I. Giammarinaro, Daniel Amador-Noguez, Stevenson, D.M., Giammarinaro, P., Young, M., Steinchen, W., Jue D. Wang, Amador Noguez, D., Mais, C.N., David M. Stevenson, Paulus, A., Stevenson, D., Christopher-Nils Mais   +27 more
core   +1 more source

Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli

FEBS Letters, Volume 599, Issue 5, Page 667-681, March 2025.
Bacteria can absorb external fatty acids to build their membranes. Working in E. coli, we show that external fatty acids inhibit internal fatty acid production through competition for membrane synthesis. This rapid negative feedback helps bacteria conserve resources and preserve membrane properties. We predict similar mechanisms exist in many bacteria.
Stefan Pieter Hendrik van den Berg, Adja Zoumaro‐Djayoon, Flora Yang, Gregory Bokinsky   +3 more
wiley   +1 more source

Guanosine tetraphosphate (ppGpp) dependence of the growth rate control of rrnB P1 promoter activity in Escherichia coli.

Journal of Biological Chemistry, 1990
We have fused the ribosomal RNA promoter P1 from the rrnB gene of Escherichia coli to lacZ and examined its guanosine tetraphosphate (ppGpp)-dependent expression at different growth rates.
V. Hernandez, H. Bremer
semanticscholar   +1 more source

The Mysterious World of Non‐Canonical Caps – What We Know and Why We Need New Sequencing Techniques

ChemBioChem, Volume 26, Issue 3, February 1, 2025.
This review describes sophisticated methodologies such as LC–MS that enabled the identification of 5’ non‐canonical RNA caps and also surveys so far developed sequencing methods, evaluating their advantages and disadvantages. It emphasizes the need for developing new, reliable sequencing techniques to identify RNA types with non‐canonical caps enabling
Flaminia Mancini, Hana Cahova
wiley   +1 more source