Extracellular Guanosine 5′-Triphosphate Induces Human Muscle Satellite Cells to Release Exosomes Stuffed With Guanosine [PDF]
Frontiers in Pharmacology, 2018 The extracellular guanosine 5′-triphosphate, GTP, has been demonstrated to be an enhancer of myogenic cell differentiation in a murine cell line, not yet in human muscle cells.
Tiziana Pietrangelo +9 more
doaj +5 more sources
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer. [PDF]
J Clin Invest, 2021 MYC stimulates both metabolism and protein synthesis, but it is unknown how cells coordinate these complementary programs. Previous work reported that in a subset of small cell lung cancer (SCLC) cell lines, MYC activates guanosine triphosphate (GTP ...
Huang F +27 more
europepmc +2 more sources
Conformations and binding pockets of HRas and its guanine nucleotide exchange factors complexes in the guanosine triphosphate exchange process. [PDF]
J Comput Chem, 2022 The human Son of Sevenless (SOS) activates the signal‐transduction protein Ras by forming the complex SOS·Ras and accelerating the guanosine triphosphate (GTP) exchange in Ras.
Xiong Y +5 more
europepmc +2 more sources
A Small Guanosine Triphosphate Binding Protein PagRabE1b Promotes Xylem Development in Poplar [PDF]
Frontiers in Plant Science, 2021 Rab GTPases are the subfamily of the small guanosine triphosphate (GTP)-binding proteins which participated in the regulation of various biological processes. Recent studies have found that plant Rabs play some specific functions.
Ying-Li Liu +8 more
doaj +2 more sources
Spectrum of neurodevelopmental disease associated with the GNAO1 guanosine triphosphate-binding region. [PDF]
Epilepsia, 2019 To characterize the phenotypic spectrum associated with GNAO1 variants and establish genotype‐protein structure‐phenotype relationships.
Kelly M +23 more
europepmc +2 more sources
Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments. [PDF]
J Cell Biol, 2018 We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species.
McIntosh JR +6 more
europepmc +2 more sources
Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells [PDF]
BiologyIntravenously transplanted mesenchymal stromal cells (MSCs) have been shown to interact with endothelial cells and to migrate to tissues. However, intracellular signals regulating MSC migration are still incompletely understood.
Melanie Giesen +4 more
doaj +2 more sources
Light-driven artificial enzymes for selective oxidation of guanosine triphosphate using water-soluble POSS network polymers. [PDF]
Organic and biomolecular chemistry, 2014 Accepted 25 Jun 2014.The light-driven artificial enzymes were constructed to realize unnatural reactions concerning bio-significant molecules. In this manuscript, the guanosine triphosphate (GTP)-selective oxidation is reported using the network polymers
Jonghwan Jeon, Kazuo Tanaka, Y. Chujo
semanticscholar +3 more sources
Elevated levels of plasma phenylalanine in schizophrenia: a guanosine triphosphate cyclohydrolase-1 metabolic pathway abnormality? [PDF]
PLoS ONE, 2014 BACKGROUND: Phenylalanine and tyrosine are precursor amino acids required for the synthesis of dopamine, the main neurotransmitter implicated in the neurobiology of schizophrenia.
Olaoluwa Okusaga +15 more
doaj +2 more sources