Adenosine triphosphate as a modulator of protein interactions and stability. [PDF]
FEBS Open BioATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Tan S, Curtis R.
europepmc +2 more sources
Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy. [PDF]
J Am Soc Nephrol, 2013 In diabetes, endothelial nitric oxide synthase (eNOS) produces superoxide anion rather than nitric oxide, referred to as "eNOS uncoupling," which may contribute to endothelial dysfunction, albuminuria, and diabetic nephropathy.
Kidokoro K +5 more
europepmc +2 more sources
An Effector of Hemoglobin Structure: The Guanosine 3', 5'-Triphosphate [PDF]
, 2012 The effect of guanosine 3', 5'-triphosphate (GTP) on the hemoglobin structure was studied by UV-visible, fluorescence and circular dichroism (CD) spectroscopies, and cyclic voltammetry.
Arefi, Mohammad Reza +11 more
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A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]
, 1988 A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
Soll, Jürgen +5 more
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Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
, 2012 Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Claire M. Peppiatt-Wildman +18 more
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Guanosine-Based Self-Assembly as an Enantioselective Catalyst Scaffold
, 2020 A self-assembled G-quadruplex formed by guanosine and borate as the chiral scaffold was used to catalyze the asymmetric Friedel–Crafts reaction in water.
Xiaolin Sun (53844) +4 more
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The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]
, 2002 Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Soll, J. +5 more
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Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
Angewandte Chemie, EarlyView.The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
wiley +2 more sources
, 2013 Luminescence fold change of the system for 1′-triphosphate (UTP), guanosine 5′-triphosphate (GTP), cytidine 5′-triphosphate (CTP), adenosine 5′-diphosphate (ADP), adenosine 5′-monophosphate (AMP), 300 mM NaCl, 2% glucose and 0.05% serum albumin (SA).
Dik-Lung Ma (103041) +9 more
core +1 more source