Results 11 to 20 of about 85,574 (298)

Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells [PDF]

Biology
Intravenously transplanted mesenchymal stromal cells (MSCs) have been shown to interact with endothelial cells and to migrate to tissues. However, intracellular signals regulating MSC migration are still incompletely understood.
Melanie Giesen, Erika Fleck, Jürgen Scheele, Tanja Nicole Hartmann, Reinhard Henschler   +4 more
doaj   +4 more sources

A Small Guanosine Triphosphate Binding Protein PagRabE1b Promotes Xylem Development in Poplar [PDF]

Frontiers in Plant Science, 2021
Rab GTPases are the subfamily of the small guanosine triphosphate (GTP)-binding proteins which participated in the regulation of various biological processes. Recent studies have found that plant Rabs play some specific functions.
Ying-Li Liu, Li-Juan Wang, Li-Juan Wang, Yu Li, Yu Li, Ying-Hua Guo, Yuan Cao, Shu-Tang Zhao, Shu-Tang Zhao   +8 more
doaj   +2 more sources

Elevated levels of plasma phenylalanine in schizophrenia: a guanosine triphosphate cyclohydrolase-1 metabolic pathway abnormality? [PDF]

PLoS ONE, 2014
BACKGROUND: Phenylalanine and tyrosine are precursor amino acids required for the synthesis of dopamine, the main neurotransmitter implicated in the neurobiology of schizophrenia.
Olaoluwa Okusaga, Olesja Muravitskaja, Dietmar Fuchs, Ayesha Ashraf, Sarah Hinman, Ina Giegling, Annette M Hartmann, Bettina Konte, Marion Friedl, Jason Schiffman, Elliot Hong, Gloria Reeves, Maureen Groer, Robert Dantzer, Dan Rujescu, Teodor T Postolache   +15 more
doaj   +2 more sources

A Putative Guanosine Triphosphate Cyclohydrolase I Named CaGCH1 Is Involved in Hyphal Branching and Fruiting Development in Cyclocybe aegerita. [PDF]

Front Microbiol, 2022
Tao N, Cheng B, Chai H, Cui X, Ma Y, Yan J, Zhao Y, Chen W.   +7 more
europepmc   +2 more sources

Extracellular Guanosine 5′-Triphosphate Induces Human Muscle Satellite Cells to Release Exosomes Stuffed With Guanosine

Frontiers in Pharmacology, 2018
The extracellular guanosine 5′-triphosphate, GTP, has been demonstrated to be an enhancer of myogenic cell differentiation in a murine cell line, not yet in human muscle cells.
Tiziana Pietrangelo, Marcello Locatelli, Francesco Piacenza   +2 more
exaly   +3 more sources

In-silico investigation reveals microbial metabolic biomarkers and their regulatory roles in hormone sensitive cancers [PDF]

Journal of Genetic Engineering and Biotechnology
Cancer burden has become a global concern, specifically with hormone-sensitive cancers (HSC). Among the various factors influencing the progress and treatment of cancers, the human microbiota plays a vital role.
Suvitha Anbarasu, Srujal Kacha, Sudha Ramaiah, Anand Anbarasu   +3 more
doaj   +2 more sources

Alpha-synuclein amyloids catalyze the degradation of ATP and other nucleotides [PDF]

Scientific Reports
Intracellular accumulation of alpha-synuclein amyloids is a main pathological hallmark in a subgroup of human neurodegenerative diseases called synucleinopathies.
Claudio Castillo-Cáceres, Esteban Nova, Rodrigo Diaz-Espinoza   +2 more
doaj   +2 more sources

Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14. [PDF]

J Biol Chem
Agogo-Mawuli PS, Sadiya I, Abramyan TM, Bosch DE, Emmitte KA, Colón-Pérez LM, Kosloff M, Siderovski DP.   +7 more
europepmc   +5 more sources

Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer. [PDF]

J Clin Invest, 2021
Huang F, Huffman KE, Wang Z, Wang X, Li K, Cai F, Yang C, Cai L, Shih TS, Zacharias LG, Chung A, Yang Q, Chalishazar MD, Ireland AS, Stewart CA, Cargill K, Girard L, Liu Y, Ni M, Xu J, Wu X, Zhu H, Drapkin B, Byers LA, Oliver TG, Gazdar AF, Minna JD, DeBerardinis RJ.   +27 more
europepmc   +3 more sources

Spectrum of neurodevelopmental disease associated with the GNAO1 guanosine triphosphate-binding region. [PDF]

Epilepsia, 2019
Kelly M, Park M, Mihalek I, Rochtus A, Gramm M, Pérez-Palma E, Axeen ET, Hung CY, Olson H, Swanson L, Anselm I, Briere LC, High FA, Sweetser DA, Undiagnosed Diseases Network, Kayani S, Snyder M, Calvert S, Scheffer IE, Yang E, Waugh JL, Lal D, Bodamer O, Poduri A.   +23 more
europepmc   +3 more sources