Results 51 to 60 of about 159,662 (351)

Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells [PDF]

, 1990
Undifferentiated and differentiated HL-60 leukemic cells possess nucleotide receptors which functionally couple to phospholipase C via pertussis toxin-sensitive guanine nucleotide-binding proteins (G-proteins).
Seifert, Roland, Wenzel-Seifert, Katharina   +1 more
core   +1 more source

Microtubule catastrophe from protofilament dynamics [PDF]

Phys. Rev. E 88, 032717 (2013), 2013
The disappearance of the guanosine triphosphate (GTP)-tubulin cap is widely believed to be the forerunner event for the growth-shrinkage transition (`catastrophe') in microtubule filaments in eukaryotic cells. We study a discrete version of a stochastic model of the GTP cap dynamics, originally proposed by Flyvbjerg, Holy and Leibler (Flyvbjerg, Holy ...
arxiv   +1 more source

Nonenzymatic Formation of Guanosine 3′ : 5′-Monophosphate from Guanosine Triphosphate

Journal of Biological Chemistry, 1974
Abstract We observed the nonenzymatic formation of guanosine 3' : 5'-monophosphate (cyclic GMP) from GTP. The reaction was dependent upon heat and was accelerated by divalent cations and creatine phosphate. The formation of cyclic GMP was greater with increased incubation time, temperature, GTP concentration, and pH. All of the divalent cations tested (
Ferid Murad, Hiroshi Kimura
openaire   +3 more sources

Tuning the Kinetic Trapping in Chemically Fueled Self‐Assembly**

ChemSystemsChem, Volume 5, Issue 1, January 2023., 2023
Dynamic molecular self‐assemblies like microtubules show dynamic instabilities. Synthetic analogs of such dynamic assemblies regulated by chemical‐fueled reaction cycles often face the challenge to display dynamic instability. In this work, we show how molecular design can be used to tune the degree of kinetically trapping to approach dynamic ...
Brigitte A. K. Kriebisch, Christine M. E. Kriebisch, Alexander M. Bergmann, Caren Wanzke, Marta Tena‐Solsona, Job Boekhoven   +5 more
wiley   +1 more source

The Universally Conserved Unconventional G Protein YchF Is Critical for Growth and Stress Response

Life, 2023
The ancient guanine nucleotide-binding (G) proteins are a group of critical regulatory and signal transduction proteins, widely involved in diverse cellular processes of all kingdoms of life. YchF is a kind of universally conserved novel unconventional G
Zhaoheng Lin, Rongfang Li, Zhiwei Han, Yi Liu, Liyang Gao, Suchang Huang, Ying Miao, Rui Miao   +7 more
doaj   +1 more source

GTP and Ca2+ Modulate the Inositol 1,4,5-Trisphosphate-Dependent Ca2+ Release in Streptolysin O-Permeabilized Bovine Adrenal Chromaffin Cells [PDF]

, 1991
The inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release was studied using streptolysin O-permeabilized bovine adrenal chromaffin cells. The IP3-induced Ca2+ release was followed by Ca2+ reuptake into intracellular compartments.
Ahnert-Hilger G., Ahnert-Hilger G., B. Stecher, Bhakdi S., Bhakdi S., Brass L. F., Chueh S.-H., Comerford J. G., Danoff S. K., Dawson A. P., Fohr K. J., G. Ahnert-Hilger, Hirata M., Hugo F., J. Scott, Joseph S. K., K. J. Föhr, Kao L.-S., Livett B., M. Gratzl, Rossier M. F., Stoehr S. J., Supattapone S., Worley P. F.   +23 more
core   +1 more source

Water‐Soluble Pd‐Imidate Complexes as Versatile Catalysts for the Modification of Unprotected Halonucleosides

The Chemical Record, Volume 22, Issue 12, December 2022., 2022
Three generations of neutral and anionic water‐soluble palladium complexes act as versatile catalysts for the modification of unprotected halonucleosides. Abstract Modification of unprotected nucleosides has been attracting continuous interest, since these building blocks themselves and their phosphate‐upgraded corresponding nucleotides have shown a ...
José Luis Serrano
wiley   +1 more source

Ginsenoside Re inhibits pacemaker potentials via adenosine triphosphate-sensitive potassium channels and the cyclic guanosine monophosphate/nitric oxide-dependent pathway in cultured interstitial cells of Cajal from mouse small intestine

Journal of Ginseng Research, 2015
Background: Ginseng belongs to the genus Panax. Its main active ingredients are the ginsenosides. Interstitial cells of Cajal (ICCs) are the pacemaker cells of the gastrointestinal (GI) tract.
Noo Ri Hong, Hyun Soo Park, Tae Seok Ahn, Hyun Jung Kim, Ki-Tae Ha, Byung Joo Kim   +5 more
doaj   +1 more source

UV resistance of nucleosides -- an experimental approach [PDF]

, 2020
The emergence of life on Earth is a highly discussed but still unsolved question. Current research underlines the importance of environments within close proximity to the Earth's surface as they can solve long-standing problems such as polymerization of nucleotides and phosphorylation of nucleosides.
arxiv   +1 more source

Transition behavior of the seizure dynamics modulated by the astrocyte inositol triphosphate noise [PDF]

, 2021
Epilepsy is a neurological disorder with recurrent seizures of complexity and randomness. Until now, the mechanism of epileptic randomness has not been fully elucidated. Inspired by the recent finding that astrocyte GTPase-activating protein (G-protein)-coupled receptors could be involved in stochastic epileptic seizures, we proposed a neuron-astrocyte
arxiv   +1 more source