Results 71 to 80 of about 40,840 (280)

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

open access: yes, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust   +9 more
core   +2 more sources

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

Ethnomedicinal uses, phytochemistry, pharmacological activities, and toxicology of the subfamily Gomphrenoideae (Amaranthaceae): A comprehensive review

open access: yesChemistry &Biodiversity, Accepted Article.
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Calculus Bovis-Fel Uris-Moschus Pharmacopuncture’s Effect on Regional Cerebral Blood Flow and Mean Arterial Blood Pressure in Rats

open access: yesJournal of Pharmacopuncture, 2013
Objectives: This study was designed to investigate the effects of Calculus Bovis-Fel Uris-Moschus pharmacopuncture (BUM) on the regional cerebral blood flow (rCBF) and the mean arterial blood pressure (MABP) in normal and cerebral ischemic rats and to ...
Park Soo-Jung   +4 more
doaj   +1 more source

Antithetical modes of and the Ca2+ sensors targeting in ANF-RGC and ROS-GC1 membrane guanylate cyclases

open access: yesFrontiers in Molecular Neuroscience, 2012
The membrane guanylate cyclase family has been branched into three subfamilies: natriuretic peptide hormone surface receptors, Ca2+-modulated neuronal ROS-GC, and Ca2+-modulated odorant surface receptor ONE-GC.
Teresa eDuda   +3 more
doaj   +1 more source

Guanylate cyclase and the ⋅NO/cGMP signaling pathway

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1999
Signal transduction with the diatomic radical nitric oxide (NO) is involved in a number of important physiological processes, including smooth muscle relaxation and neurotransmission. Soluble guanylate cyclase (sGC), a heterodimeric enzyme that converts guanosine triphosphate to cyclic guanosine monophosphate, is a critical component of this signaling ...
John W. Denninger, Michael A. Marletta
openaire   +3 more sources

Soluble Guanylate Cyclase Conformational Regulation [PDF]

open access: yesBiophysical Journal, 2009
Nitric Oxide (NO) is an important signaling molecule that is involved in many physiological processes. In cells, NO is produced by Nitric Oxide Synthases (NOs) then bind to its principal receptor Soluble Guanylate Cyclase (sGC). Upon NO binding, sGC activity increases as it catalyzes the conversion of its substrate GTP to cGMP.
Jasmin Kristianto   +2 more
openaire   +2 more sources

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions

open access: yesChemistry – A European Journal, EarlyView.
Highly water‐soluble Npy‐sulfenate functions as an efficient oxidizing agent for the formation of disulfide bonds in thiol‐containing peptides. The Npy‐sulfenate can be used to form a disulfide bond with a thiol‐containing peptide produced by thiol‐additive‐free NCL, thereby facilitating the one‐pot synthesis of adrenomedullin.
Akihiro Taguchi   +8 more
wiley   +1 more source

Neurons exposed to ammonia reproduce the differential alteration in nitric oxide modulation of guanylate cyclase in the cerebellum and cortex of patients with liver cirrhosis

open access: yesNeurobiology of Disease, 2005
The activation of soluble guanylate cyclase by nitric oxide is increased in the frontal cortex but is reduced in the cerebellum of patients who died with liver cirrhosis.
Regina Rodrigo   +2 more
doaj  

ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. [PDF]

open access: yes, 2017
There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Li, Peng   +3 more
core   +2 more sources

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