Results 81 to 90 of about 40,840 (280)
ESC Heart Failure, EarlyView.AIM This analysis provides a comparison of the efficacy of initial mono and combination therapy in patients with PAH and cardiovascular comorbidities or with risk factors of HFpEF (heart failure with preserved ejection fractioin).METHOD Data from the European COMPERA registry were used for a matched pair analysis.
Dirk Skowasch +20 more
wiley +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Indications and efficacy of drugs used for the treatment of pulmonary hypertension are considered. Stages of the treatment of pulmonary arterial hypertension are discussed, including maintenance therapy, specific therapy with calcium channel blockers ...
E. L. Trisvetova, S. V. Gubkin
doaj +1 more source
Physiological Reports, 2022 Acute pulmonary embolism (PE) does not always resolve after treatment and can progress to chronic thromboembolic disease (CTED) or the more severe chronic thromboembolic pulmonary hypertension (CTEPH).
John Zagorski +4 more
doaj +1 more source
European Journal of Heart Failure, EarlyView.Baseline characteristics for the vericiguat global study in participants with chronic heart failure (VICTOR) trial. ARNI, angiotensin receptor/neprilysin inhibitor; CRT, cardiac resynchronization therapy; eGFR, estimated glomerular filtration rate; GDMT, guideline‐directed medical therapy; HF, heart failure; HFrEF, heart failure with reduced ejection ...
Clara I. Saldarriaga +21 more
wiley +1 more source
Bicarbonate and Ca2+ sensing modulators activate photoreceptor ROS-GC1 synergistically
Frontiers in Molecular Neuroscience, 2016 Photoreceptor ROS-GC1, a prototype subfamily member of the membrane guanylate cyclase family, is a central component of phototransduction. It is a single transmembrane-spanning protein, composed of modular blocks.
Teresa eDuda +3 more
doaj +1 more source
Vericiguat: The Fifth Harmony of Heart Failure with Reduced Ejection Fraction
Journal of Cardiovascular Development and Disease, 2023 Heart failure with reduced ejection fraction is a chronic and progressive syndrome that continues to be a substantial financial burden for health systems in Western countries. Despite remarkable advances in pharmacologic and device-based therapy over the
Luigi Falco +8 more
doaj +1 more source
European Journal of Heart Failure, EarlyView.Abstract This clinical consensus statement revisits the role of left ventricular ejection fraction (LVEF) as a measurement of cardiac function, a prognostic marker and a major criterion to classify patients with heart failure, and gives new advice for clinical practice.
Giuseppe M.C. Rosano +20 more
wiley +1 more source
BMC Cardiovascular Disorders, 2022 Background Titin phosphorylation contributes to left ventricular (LV) diastolic dysfunction. The independent effects of inflammation on the molecular pathways that regulate titin phosphorylation are unclear.
Ashmeetha Manilall +6 more
doaj +1 more source
Role of guanylyl cyclase modulation in mouse cone phototransduction [PDF]
, 2011 A negative phototransduction feedback in rods and cones is critical for the timely termination of their light responses and for extending their function to a wide range of light intensities. The calcium feedback mechanisms that modulate phototransduction
Chen, Jeannie +2 more
core +2 more sources
European Journal of Heart Failure, EarlyView.This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.
Yuxiang Luo +8 more
wiley +1 more source