Results 81 to 90 of about 4,330,253 (294)
Guideline of guidelines: Peyronie's disease
BJU InternationalObjective To compare major Peyronie's disease (PD) guidelines, highlight key similarities and differences among panel recommendations, and identify areas requiring further research. Methods An extensive review was conducted to analyse ...
Francesco Chierigo +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
UNIMARC Guidelines for Manuscripts
, 2015 These Guidelines are applicable to manuscript materials of most kinds, produced at whatever historical or contemporary time or date; this includes manuscript books, letters, speeches, sermons, etc., typescript, typewriter or print-out from a computer ...
IFLA UNIMARC Strategic Programme
core +1 more source
, 2014 JEWLScholar is the institutional repository of Middle Tennessee State University (MTSU), providing open access to scholarly research conducted at MTSU.
JEWLScholar
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Rationing cancer treatment: a qualitative study of perceptions of legitimate limit-setting
BMC Health Services Research, 2018 Background Governments are facing tough choices about whether to fund new, promising but highly expensive drugs within the public healthcare system. Decisions that some drugs are not sufficiently beneficial relative to their cost to merit public funding ...
Eli Feiring, Hege Wang
doaj +1 more source
Clinical guidelines: Using clinical guidelines
BMJ, 1999 This is the last in a series of four articles on issues in the development and use of clinical guidelines In this series we have discussed the advantages and disadvantages of clinical guidelines, methods of guideline development, and the legal, political, and emotional aspects of guidelines. Assuming that the overriding purpose of clinical guidelines
Feder G +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
MedUNAB, 2015 Introducción: El uso de las guías de mejores prácticas promueve cuidado basado en la evidencia y calidad en los resultados sanitarios. Tradicionalmente, las guías de mejores prácticas fueron diseñadas para ser usadas como un recurso escrito de forma ...
Rita Wilson. RN., M Ed., MN. +2 more
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