Results 101 to 110 of about 4,454,225 (289)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Editor's Choice -- European Society for Vascular Surgery (ESVS) 2025 Clinical Practice Guidelines on the Management of Vascular Trauma

OBJECTIVE: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for the care of patients with vascular trauma with the aim of assisting physicians in selecting the optimal management strategy.METHODS: The guidelines
Dubose, Joseph J.,, Vega de Ceniga, Melina, Boyle, Jonathan R.,, Ruffino, M.A., Blair, Paul,, de Ceniga, Melina Vega,, Van Herzeele, Isabelle,, Kakkos, Stavros K, Civil, Ian D.S., Jongkind, V., Piffaretti, G., ESVS Guidelines Committee, [missing], Wahlgren, Carl Magnus,, DuBose, Joseph J, Twine, Christopher P.,, Van Herzeele, Isabelle, Boyle, Jonathan R., DuBose, J.J., Heim, C., Wahlgren, C.M., Mitchell, Erica L, Piffaretti, Gabriele,, Wanhainen, Anders,, Wipper, S., Mees, BME, Antoniou, George A., Trimarchi, Santi,, Wipper, Sabine, Dias, N.V., Engelhardt, Michael,, Coscas, Raphael,, Aylwin, C., Mitchell, E.L., Jorgensen, Joakim, Boyle, Jonathan R, Gaarder, C., Dubose, Joseph J., Civil, Ian D. S.,, Wipper, Sabine,, Kakkos, S.K., Dias, Nuno V., Civil, Ian D. S., Ruffino, Maria Antonella, Wanhainen, A., Vikatmaa, Pirkka, Mees, Barend M.E., Mees, Barend M. E.,, Aylwin, Christopher, Ruffino, Maria Antonella,, Ricco, Jean-Baptiste,, de Ceniga, Melina Vega, Kakkos, Stavros K.,, Twine, Christopher P, Mees, Barend M. E., Dias, Nuno, V, Vikatmaa, P., Antoniou, G.A., Brohi, Karim, Coscas, Raphaël, Civil, Ian D S, Davenport, Ross A, Heim, Catherine, Blair, P., Engelhardt, M., Coscas, R., Heim, Catherine,, Davidovic, Lazar B, Wanhainen, Anders, Trimarchi, Santi, Dias, Nuno, V,, Ricco, J.B., ?, ?, Mcgreevy, David T., Gaarder, Christine,, Davenport, Ross A.,, Jongkind, Vincent,, Antoniou, George A.,, Davenport, R.A., Twine, C.P., Piffaretti, Gabriele, Wahlgren, Carl Magnus, Trimarchi, S., McGreevy, David T, Blair, Paul, Antoniou, George A, Vega de Ceniga, M., Davenport, Ross A., Jorgensen, Joakim,, McGreevy, D.T., Aylwin, Christopher,, Van Herzeele, I., JørgensenIn, Joakim, Mees, Barend M E, Davidovic, Lazar B.,, Twine, Christopher P., Jongkind, Vincent, Dias, Nuno V, Ricco, Jean-Baptiste, Mitchell, Erica L.,, Brohi, K., Davidovic, Lazar B., Vikatmaa, Pirkka,, Boyle, J.R., Engelhardt, Michael, Mitchell, Erica L., Jørgensen, J., Mcgreevy, David T.,, Gaarder, Christine, Brohi, Karim,, Kakkos, Stavros K., ESVS Guidelines Committee, George A., Davidovic, L.B., Civil, IDS, Dias, Nuno, Jørgensen, Joakim   +114 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Guidelines on Open Publication

Guidelines on publishing research results in an open manner, for projects funded by SESAR 3 Joint Undertaking. These guidelines are a part of the Engage 2 project work on application of open science principles in air traffic management ...
Bolic, T.
core   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Guideline of Guidelines [PDF]

BJU International, 2014
openaire   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Author Guidelines

Ornamental Horticulture, 2020
Author Guidelines
doaj   +6 more sources