Results 101 to 110 of about 4,330,253 (294)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Child support and arrearage guidelines /
Title from cover.; "Pursuant to CSG [sect.] 46b-215a ..."--T.p.
Connecticut. Commission for Child Support Guidelines.
core +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Guidelines for Conducting Joint Evaluations of Humanitarian Action
A joint evaluation is when different agencies work together to evaluate and review their response to an emergency. This helps agencies increase accountability and transparency, to learn from one another, and to coordinate future responses.
core
Taking stock of existing evidence and closing evidence gaps – Reflections from the National Institute for Health and Care Excellence (NICE) [PDF]
Kay Nolan
doaj +1 more source
Introducción: La búsqueda de prácticas basadas en la evidencia ha estimulado acciones por parte de un número de grupos a nivel mundial para desarrollar herramientas de conocimiento.
Irmajean Bajnok, RN., MScN., PhD. +3 more
doaj

