Results 91 to 100 of about 380,579 (360)
The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
Cytoskeleton, EarlyView.ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou +6 more
wiley +1 more source
Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs
Frontiers in Microbiology, 2019 Here, we have established an antigen-specific single B cell sorting and monoclonal antibody (mAb) cloning platform for analyzing immunization- or viral infection-elicited antibody response at the clonal level in guinea pigs.
Lin Lei +9 more
doaj +1 more source
Plastic and Reconstructive Surgery - Global Open, 2022 Lilit Garibyan, MD, PhD +1 more
openaire +3 more sources
A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide–induced proarrhythmic early afterdepolarizations [PDF]
, 2017 Exposure to carbon monoxide (CO) causes early afterdepolarization arrhythmias. Previous studies in rats indicated arrhythmias arose due to augmentation of the late Na+ current.
Chris Peers +8 more
core +2 more sources
ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay
Cytoskeleton, EarlyView.ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński +2 more
wiley +1 more source
Parasites & Vectors, 2014 Background Brazilian spotted fever (BSF), caused by the bacterium Rickettsia rickettsii, is the deadliest spotted fever of the world. In most of the BSF-endemic areas, capybaras (Hydrochoerus hydrochaeris) are the principal host for the tick Amblyomma ...
Felipe S Krawczak +5 more
doaj +1 more source
ChemMedChem, EarlyView.Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti +4 more
wiley +1 more source
Comparative analysis of rodent lens morphometrics and biomechanical properties
Frontiers in OphthalmologyIntroductionProper ocular lens function requires biomechanical flexibility, which is reduced during aging. As increasing lens size has been shown to correlate with lens biomechanical stiffness in aging, we tested the hypothesis that whole lens size ...
Sepideh Cheheltani +9 more
doaj +1 more source
Providing Homes For The Homeless - The Viable Alternative [PDF]
Tropicultura, 1994 Guinea pig Cavia porcellus farming for meat production remains a marginalised activity in Cameroon in spite of the advantages this specie offers. With the view to promote its production, a national countrywide survey was carried out in order to evaluate ...
Herbstein, D.
doaj
Journal of Pharmacological Sciences, 2008 The contribution of the T-type Ca2+ current to cardiac pacemaking was examined in isolated right atrial tissue from the mouse, guinea pig, and rabbit using a specific blocker, R(−)-efonidipine.
Hikaru Tanaka +7 more
doaj +1 more source